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CORC

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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
收藏  |  浏览/下载：76/0  |  提交时间：2022/02/14
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04
Sexual dimorphism of DNA and histone methylation profiles in the gonads of the olive flounder Paralichthys olivaceus 期刊论文
FISH PHYSIOLOGY AND BIOCHEMISTRY, 2021, 页码: 12
作者:  Liu, Yan;  Wang, Wenxiang;  Liang, Shaoshuai;  Wang, Lijuan;  Zou, Yuxia
收藏  |  浏览/下载：95/0  |  提交时间：2021/08/17
DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation 期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:  Shuai, Lin;  Li, Bo-Han;  Jiang, Hao-Wen;  Yang, Lin;  Li, Jia
收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/01
Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines 期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 213, 页码: 10
作者:  Hao, Bingbing;  Sun, Mingwei;  Zhang, Min;  Zhao, Xiaoxiao;  Zhao, Lei
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01

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