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上海药物研究所 [24]
山东大学 [4]
西安交通大学 [3]
复旦大学上海医学院 [3]
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期刊论文 [35]
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5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Category, process, and recommendation of design in an interactive evolutionary computation interior design experiment: a data-driven study
期刊论文
AI EDAM-ARTIFICIAL INTELLIGENCE FOR ENGINEERING DESIGN ANALYSIS AND MANUFACTURING, 2020, 卷号: 34, 期号: 2, 页码: 233-247
作者:
Huang, Weixin
;
Su, Xia
;
Wu, Mingbo
;
Yang, Lijing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/07/09
Clustering
color combination
design experiment
interactive evolutionary computation
recommendation system
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 5, 页码: 2348-2361
作者:
Li, Shiliang
;
Qin, Chun
;
Cui, Shichao
;
Xu, Hongling
;
Wu, Fangshu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes.
期刊论文
Journal of medicinal chemistry, 2019
作者:
Shiliang Li
;
Chun Qin
;
Shichao Cui
;
Hongling Xu
;
Fangshu Wu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/17
A series of camptothecin prodrugs exhibit HDAC inhibition activity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 16, 页码: 4706-4715
作者:
Zhu, Qiwen
;
Yu, Xumeng
;
Shen, Qianqian
;
Zhang, Qiumeng
;
Su, Mingbo
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Camptothecin
HDAC
SAHA
Prodrug
Clinical and Physiological Characterization of Elevated Plasma Glucagon-Like Peptide-1 Levels (Hyperglipemia) in a Dipeptidyl Peptidase IV Mutation Carrier
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Zhao, Dandan
;
Zhao, Shaoqian
;
Wang, Xiao
;
Su, Mingbo
;
Liu, Wen
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
dipeptidyl peptidase IV
glucagon-like peptide-1
beta-cell function
type 2 diabetes
incretin effect
Ultralight, Recoverable, and High-Temperature-Resistant SiC Nanowire Aerogel
期刊论文
ACS NANO, 2018, 卷号: 12, 页码: 3103-3111
作者:
Su, Lei
;
Wang, Hongjie
;
Niu, Min
;
Fan, Xingyu
;
Ma, Mingbo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/11/26
ceramic nanowire aerogel
heat resistance
oil absorption
recoverable compressibility
ultralow density
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 128, 页码: 293-299
作者:
Wang, Jiang
;
Su, Mingbo
;
Li, Tingting
;
Gao, Anhui
;
Yang, Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
HDAC inhibitor
Anti-proliferation
Western blot
Thienopyrimidine
Structure-activity relationship
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