×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [29]
上海生物化学与细胞... [18]
中国科学院大学 [7]
厦门大学 [5]
北京大学 [5]
复旦大学上海医学院 [5]
更多...
内容类型
期刊论文 [101]
学位论文 [3]
发表日期
2022 [1]
2021 [4]
2020 [9]
2019 [11]
2018 [12]
2017 [7]
更多...
学科主题
Cell Biolo... [6]
Science & ... [3]
Biochemist... [2]
Biochemist... [1]
Genetics &... [1]
Hematology [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共104条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/02/14
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Sexual dimorphism of DNA and histone methylation profiles in the gonads of the olive flounder Paralichthys olivaceus
期刊论文
FISH PHYSIOLOGY AND BIOCHEMISTRY, 2021, 页码: 12
作者:
Liu, Yan
;
Wang, Wenxiang
;
Liang, Shaoshuai
;
Wang, Lijuan
;
Zou, Yuxia
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/08/17
DNA methylation
Sex difference
Olive flounder Paralichthys olivaceus
DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation
期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:
Shuai, Lin
;
Li, Bo-Han
;
Jiang, Hao-Wen
;
Yang, Lin
;
Li, Jia
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/08/17
Smyd1 is essential for myosin expression and sarcomere organization in craniofacial, extraocular, and cardiac muscles
期刊论文
JOURNAL OF GENETICS AND GENOMICS, 2021, 卷号: 48, 期号: 3, 页码: 208-218
作者:
Jiao, Shuang
;
Xu, Rui
;
Du, Shaojun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/09/18
Smyd1
Myosin
Sarcomere
Craniofacial muscle
Cardiac muscle
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
;
Niu, Ao
;
Li, Yuanqing
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Single-cell RNA sequencing of t(8;21) acute myeloid leukemia for risk prediction
期刊论文
ONCOLOGY REPORTS, 2020, 卷号: 43, 期号: 4, 页码: 1278-1288
作者:
Xiong, Qian
;
Huang, Sai
;
Li, Yong-Hui
;
Lv, Na
;
Lv, Chao
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/10
acute myeloid leukemia
t(8
21)
single-cell RNA-sequencing
prognosis
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:
Min, Wenjian
;
Hou, Zeng
;
Zhang, Fang
;
Xie, Shengnan
;
Yuan, Kai
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
Histone methylation
Lysine methyltransferase
SET7
Small-molecule inhibitor
Virtual screening
©版权所有 ©2017 CSpace - Powered by
CSpace