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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:71/0  |  提交时间:2021/08/17
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation 期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:  Liu, Shan-Kui;  Hao, Haifang;  Bian, Yuan;  Ge, Yong-Xi;  Lu, Shengyuan
收藏  |  浏览/下载:58/0  |  提交时间:2021/05/24
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 10
作者:  Fan, Yafei;  Chen, Hangfei;  Mu, Ning;  Wang, Wengui;  Zhu, Kongkai
收藏  |  浏览/下载:20/0  |  提交时间:2021/05/24
Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011 期刊论文
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6
作者:  Bao, Jie;  Li, Xiu-Xiu;  He, Fei;  Zhang, Xiaoyong;  Zhu, Kongkai
收藏  |  浏览/下载:15/0  |  提交时间:2020/12/24
Spiroalanpyrroids A and B, sesquiterpene alkaloids with a unique spiro-eudesmanolide-pyrrolizidine skeleton from Inula helenium 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 2, 页码: 303-309
作者:  Cai, You-Sheng;  Wu, Zi;  Zheng, Xiao-Qin;  Wang, Cong;  Wang, Jian-Rong
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Song, Jia-Li;  Wang, Yin-Yin
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/01
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01


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