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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2020     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5 作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya 收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24 SMYD2 inhibitors  Thermal shift assay  Structure-activity relationships   Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X. 收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10 作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing 收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 Histone methylation  SET7  Small-molecule inhibitor  Virtual screening  Molecular probe   Single-cell RNA sequencing of t(8;21) acute myeloid leukemia for risk prediction 期刊论文 ONCOLOGY REPORTS, 2020, 卷号: 43, 期号: 4, 页码: 1278-1288 作者:  Xiong, Qian;  Huang, Sai;  Li, Yong-Hui;  Lv, Na;  Lv, Chao 收藏  |  浏览/下载：57/0  |  提交时间：2020/12/10 acute myeloid leukemia  t(8  21)  single-cell RNA-sequencing  prognosis   Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10 作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai 收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 Histone methylation  Lysine methyltransferase  SET7  Small-molecule inhibitor  Virtual screening   Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines 期刊论文 JOURNAL OF PROTEOMICS, 2020, 卷号: 213, 页码: 10 作者:  Hao, Bingbing;  Sun, Mingwei;  Zhang, Min;  Zhao, Xiaoxiao;  Zhao, Lei 收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 Lysine methylome  Quantitative proteomics  EZH2  Diffuse large B cell lymphoma  PTM crosstalk   Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63 作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua 收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 polycomb repressive complex 2  EZH2-EED interaction inhibitor  virtual screening  molecular dynamics simulation   The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文 CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542 作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda 收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24 WDR5  MLL1  histone methyltransferase  small-molecular inhibitor  epigenetics  human acute leukemia   Association analysis of KMT2D copy number variation as a positional candidate for growth traits 期刊论文 GENE, 2020, 卷号: 753 作者:  Cheng, Jie;  Jiang, Rui;  Yang, Yu;  Cao, Xiukai;  Huang, Yongzhen 收藏  |  浏览/下载：11/0  |  提交时间：2020/11/25 Copy number variations  KMT2D  Association analysis  Growth traits