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浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X. 收藏  |  浏览/下载：101/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63 作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua 收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 polycomb repressive complex 2  EZH2-EED interaction inhibitor  virtual screening  molecular dynamics simulation   AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian 收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing   Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 302-310 作者:  Zhu, Mao-rong;  Du, Dao-hai;  Hu, Jun-chi;  Li, Lian-chun;  Liu, Jing-qiu 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 PRC2  EZH2  EED  protein-protein interaction  fluorescence polarization  high-throughput screening  apomorphine hydrochloride  oxyphenbutazone  nifedipine  ergonovine maleate   developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文 actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302 作者:  Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu 收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01 PRC2  EZH2  EED  protein-protein interaction  fluorescence polarization  high-throughput screening  apomorphine hydrochloride  oxyphenbutazone  nifedipine  ergonovine maleate   靶向EZH2-EED蛋白相互作用界面的药物发现与机制研究 会议论文 作者:  孔祥谦;  陈丽敏;  蒋华良;  罗成 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 表观遗传  EZH2-EED相互作用  抑制剂