CORC

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CORC

浏览/检索结果: 共16条，第1-10条 帮助

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Structural basis of ketamine action on human NMDA receptors 期刊论文
NATURE, 2021, 卷号: 596, 期号: 7871, 页码: 301-+
作者:  Zhang, Youyi;  Ye, Fei;  Zhang, Tongtong;  Lv, Shiyun;  Zhou, Liping
收藏  |  浏览/下载：26/0  |  提交时间：2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：71/0  |  提交时间：2021/08/17
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:  Zhang Fengcai;  Sun Zhongya;  Liao Liping;  Zuo Yu;  Zhang Dan
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:  Zhang, Rukang;  Wang, Jiang;  Zhao, Liang;  Liu, Shien;  Du, Daohai
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302
作者:  Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu
收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01
Identification of novel ezh2 inhibitors through pharmacophore-based virtual screening and biological assays 期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:  Wu, Yunlong;  Hu, Junchi;  Ding, Hong;  Chen, Limin;  Zhang, Yuanyuan
收藏  |  浏览/下载：37/0  |  提交时间：2019/05/09
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:  Wu, Yunlong;  Hu, Junchi;  Ding, Hong;  Chen, Limin;  Zhang, Yuanyuan
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 22, 页码: 9512-9521
作者:  Kong, Xiangqian;  Chen, Limin;  Jiao, Lianying;  Jiang, Xiangrui;  Lian, Fulin
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08

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