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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study
期刊论文
CANCER MEDICINE, 2022
作者:
Yu, Xiaoqing
;
Si, Jinfei
;
Wei, Jingwen
;
Wang, Yanling
;
Sun, Yan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
EGFR-TKIs
non-small cell lung cancer (NSCLC)
real-world study
survival outcome
Baseline anemia predicts a poor prognosis in patients with non-small cell lung cancer with epidermal growth factor receptor mutations: a retrospective study
期刊论文
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wei, Jingwen
;
Xiang, Jing
;
Hao, Yue
;
Si, Jinfei
;
Wang, Wenxian
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/22
Anemia
Epidermal growth factor receptor
Epidermal growth factor receptor tyrosine kinase inhibitors
Non-small cell lung cancer
Targeting KRAS mutant cancers: from druggable therapy to drug resistance
期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:
Zhu, Chunxiao
;
Guan, Xiaoqing
;
Zhang, Xinuo
;
Luan, Xin
;
Song, Zhengbo
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
KRAS mutations
Druggable
Resistance
Combination therapy
Efficacy and safety of anlotinib with and without EGFR-TKIs or immunotherapy in the treatment of elder patients with non-small-cell lung cancer: a retrospective study
期刊论文
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wang, Wenxian
;
Shao, Lan
;
Xu, Yibing
;
Song, Zhengbo
;
Lou, Guangyuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/23
Non-small cell lung cancer
Prognosis
Angiogenesis
Tyrosine kinase inhibitors
Correlation of PD-L1 Expression with Clinicopathological and Genomic Features in Chinese Non-Small-Cell Lung Cancer
期刊论文
JOURNAL OF ONCOLOGY, 2022, 卷号: 2022
作者:
Li, Yue
;
Li, Chong
;
Jiang, Ya
;
Han, Xue
;
Liu, Sisi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
A nomogram model based on peripheral blood lymphocyte subsets to assess the prognosis of non-small cell lung cancer patients treated with immune checkpoint inhibitors
期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2021
作者:
Xu, Xiaoling
;
Wang, Ding
;
Chen, Wei
;
Li, Na
;
Suwinski, Rafal
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/02/14
Immune checkpoint inhibitor (ICI)
non-small cell lung cancer (NSCLC)
peripheral blood lymphocyte subsets
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
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