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CORC

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AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:  Liu, Xiaoyun;  Li, Wei;  Zhang, Yifan;  Jian, Yong;  Zhao, Qianyu
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas 期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:  Zhang, Qing;  Liu, Jian-He;  Liu, Jing-Li;  Qi, Chun-Ting;  Yan, Lei
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
作者:  Wang, Hui-Li;  Liu, Yan-Chun;  Long, Ming-Peng;  Zheng, Chuan;  Yang, Jia-Hui
收藏  |  浏览/下载：95/0  |  提交时间：2019/11/07
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308
作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin
收藏  |  浏览/下载：60/0  |  提交时间：2020/07/01
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S) 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:  Li, Qiannan;  Zhang, Tao;  Li, Shiliang;  Tong, Linjiang;  Li, Junyu
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
EGFR  mutant  inhibitor  C797S  
Design, synthesis and biological study of potent and covalent HER-2 tyrosine kinase inhibitors with low cytotoxicity in vitro 期刊论文
CHEMICAL PAPERS, 2019, 卷号: 73, 期号: 6, 页码: 1333-1345
作者:  Jin, Shuyu;  Sun, Xiuyun;  Liu, Dan;  Xie, Hua;  Rao, Yu
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01

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