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CORC

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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：61/0  |  提交时间：2022/01/18
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
EGFR  NSCLC  C797S  
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi
收藏  |  浏览/下载：61/0  |  提交时间：2020/12/24
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01
BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation 期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:  Yin, Weimin;  Zhao, Yuge;  Kang, Xuejia;  Zhao, Pengfei;  Zhao, Xuhong
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01
Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC 期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 1, 页码: 241-250
作者:  Zhang, Yan;  Yang, Xinying;  Liu, Hongchun;  Cai, Minghui;  Yang Shentu
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:  Liu, Xiaoyun;  Li, Wei;  Zhang, Yifan;  Jian, Yong;  Zhao, Qianyu
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas 期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:  Zhang, Qing;  Liu, Jian-He;  Liu, Jing-Li;  Qi, Chun-Ting;  Yan, Lei
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01

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