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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文 CANCER LETTERS, 2024, 卷号: 582, 页码: 15 作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia 收藏  |  浏览/下载：2/0  |  提交时间：2024/04/07 Acquired resistance  Cancer  NSCLC  JC-010a  SHP2   Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480 作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju 收藏  |  浏览/下载：136/0  |  提交时间：2020/09/29 bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability   Nanotechnology-mediated immunochemotherapy with Ingenol-3-Mebutate for Systematic Anti-tumor Effects 期刊论文 JOURNAL OF CONTROLLED RELEASE, 2019, 卷号: 304, 页码: 242-258 作者:  Yu, Mian;  Zhao, Miaoqing;  Yu, Rilei;  Chu, Shaochen;  Xu, Jiahao 收藏  |  浏览/下载：14/0  |  提交时间：2019/12/11 Ingenol-3-Mebutate  Immunotherapy  Nanoparticle  Small molecule drug   Design, synthesis and activity of Mnk1 and Mnk2 selective inhibitors containing thieno[2,3-d]pyrimidine scaffold 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 735-751 作者:  Jin, Xin;  Merrett, James;  Tong, Sheng;  Flower, Bartholomew;  Xie, Jianling 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Mnk  eIF4E inhibition  Thieno[2,3-d]pyrimidine  Selective inhibitor   Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33 作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao 收藏  |  浏览/下载：22/0  |  提交时间：2017/07/10 PTP1B  Bromophenol  Saccharide  Selectivity  Permeability   Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 8 作者:  Liu, Ming;  Chen, Fangling;  Yu, Rilei;  Zhang, Weiyi;  Han, Mei 收藏  |  浏览/下载：6/0  |  提交时间：2019/08/19 3-O-angeloyl-20-O-acetyl ingenol  PEP008  20-O-acetyl-ingenol-3-angelate  ingenol mebutat  apoptosis  chronic myeloid leukemia   Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 8 作者:  Liu, Ming;  Chen, Fangling;  Yu, Rilei;  Zhang, Weiyi;  Han, Mei 收藏  |  浏览/下载：3/0  |  提交时间：2018/12/07 3-O-angeloyl-20-O-acetyl ingenol  PEP008  20-O-acetyl-ingenol-3-angelate  ingenol mebutat  apoptosis  chronic myeloid leukemia   Pharmacokinetics in Vitro and in Vivo of Two Novel Prodrugs of Oleanolic Acid in Rats and Its Hepatoprotective Effects against Liver Injury Induced by CCl4 期刊论文 MOLECULAR PHARMACEUTICS, 2016, 卷号: 13, 期号: 5, 页码: 1699-1710 作者:  Yu, Zongjiang;  Sun, Weizhi;  Peng, Weibing;  Yu, Rilei;  Li, Guoqiang 收藏  |  浏览/下载：25/0  |  提交时间：2016/07/12 oleanolic acid (OA)  prodrug  hepatoprotective  pharmacokinetics  biodistribution   Synthesis and evaluation of novel non-covalent binding quinazoline glycoside derivatives targeting the L858R and T790M variants of EGFR 期刊论文 RSC ADVANCES, 2016, 卷号: 6, 期号: 43, 页码: 36857-36862 作者:  Zhang, Renshuai;  Chen, Shaopeng;  Zhang, Xiaowei;  Yu, Rilei;  Wan, Shengbiao 收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08