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Sheep tail fat inhibits the proliferation of non-small-cell lung cancer cells in vitro and in vivo 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Xu, Changzhi;  Zhang, Lanlan;  He, Huimin;  Liu, Xiaoyi;  Pei, Xinxin
收藏  |  浏览/下载:25/0  |  提交时间:2022/12/23
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载:28/0  |  提交时间:2021/12/16
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
收藏  |  浏览/下载:32/0  |  提交时间:2021/12/01
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载:16/0  |  提交时间:2021/12/16
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics 期刊论文
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:  Steinbrueck, Axel;  Sedgwick, Adam C.;  Han, Hai-Hao;  Zhao, Michael Y.;  Sen, Sajal
收藏  |  浏览/下载:39/0  |  提交时间:2021/06/11
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie
收藏  |  浏览/下载:42/0  |  提交时间:2021/06/11
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载:35/0  |  提交时间:2021/05/24
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping
收藏  |  浏览/下载:68/0  |  提交时间:2021/05/24
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载:20/0  |  提交时间:2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:  Uche, Fidelia Ijeoma;  Guo, Xiaozhen;  Okokon, Jude;  Ullah, Imran;  Horrocks, Paul
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24


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