CORC

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CORC

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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei
收藏  |  浏览/下载：7/0  |  提交时间：2023/11/10
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:  Zhang, Lin;  Li, Ling;  Wang, Xia;  Liu, Huimin;  Zhang, Yibin
收藏  |  浏览/下载：21/0  |  提交时间：2022/12/23
Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载：16/0  |  提交时间：2022/12/23
Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14
作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong
收藏  |  浏览/下载：30/0  |  提交时间：2021/11/01
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：37/0  |  提交时间：2021/08/17
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:  Qi, Si-Min;  Dong, Jinyun;  Xu, Zhi-Yuan;  Cheng, Xiang-Dong;  Zhang, Wei-Dong
收藏  |  浏览/下载：47/0  |  提交时间：2021/06/15
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:  Chen, Yun;  Ning, Yi;  Bai, Gang;  Tong, Linjiang;  Zhang, Tao
收藏  |  浏览/下载：19/0  |  提交时间：2021/05/24
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua
收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01
FAK-targeting PROTAC as a chemical tool for the investigation of non-enzymatic FAK function in mice 期刊论文
Protein Cell, 2020, 卷号: 11, 期号: 7, 页码: 534-539
作者:  Hongying Gao;  Zheng CW(郑春伟);  Jian Du;  Yue Wu;  Yonghui Sun
收藏  |  浏览/下载：5/0  |  提交时间：2021/10/26

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