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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations 期刊论文 BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298 作者:  Zhu, Kongkai;  Tao, Hongrui;  Song, Jia-Li;  Jin, Lu;  Zhang, Yuanyuan 收藏  |  浏览/下载：129/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Arginine methylation  Virtual screening  Molecular docking  Molecular dynamics simulation   Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483 作者:  Zhu, Kongkai;  Jiang, Chengshi;  Tao, Hongrui;  Liu, Jingqiu;  Zhang, Hua 收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Resynthesis  Virtual screening  Molecular docking  Molecular dynamics simulation   Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758 作者:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 DOT1L  MLL-rearranged leukemia  AlphaLISA  HTS  Novel inhibitors   Measurement and prediction of bioconcentration factors of organophosphate flame retardants in common carp (Cyprinus carpio) 期刊论文 ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 166, 页码: 270-276 作者:  Bekele, Tadiyose Girma;  Zhao, Hongxia;  Wang, Yan;  Jiang, Jingqiu;  Tan, Feng 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/02 Organophosphate flame retardants  Common carp  Bioconcentration  Tissue distribution  QSAR   Occurrence and profiles of halogenated phenols, polybrominated diphenyl ethers and hydroxylated polybrominated diphenyl ethers in the effluents of waste water treatment plants around Huang-Bo Sea, North China. 期刊论文 The Science of the total environment, 2018, 卷号: 622-623, 页码: 1-7 作者:  Jiang Jingqiu;  Zhao Hongxia;  Sun Shibin;  Wang Yuntao;  Liu Sisi 收藏  |  浏览/下载：11/0  |  提交时间：2019/12/02 Effluent,Halogenated phenols,OH-PBDEs,PBDEs,Waste water treatment plant   developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文 actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302 作者:  Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu 收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01 PRC2  EZH2  EED  protein-protein interaction  fluorescence polarization  high-throughput screening  apomorphine hydrochloride  oxyphenbutazone  nifedipine  ergonovine maleate