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A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng
收藏  |  浏览/下载:24/0  |  提交时间:2021/12/01
DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation 期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:  Shuai, Lin;  Li, Bo-Han;  Jiang, Hao-Wen;  Yang, Lin;  Li, Jia
收藏  |  浏览/下载:19/0  |  提交时间:2021/08/17
Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459
作者:  Liu Na;  Guo Siqi;  Liu Junfang;  Chen Yantao;  Xu Xiaoming
收藏  |  浏览/下载:20/0  |  提交时间:2020/12/24
Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354
作者:  Xu Xiaoming;  Guo Siqi;  Zhang Jing;  Chen Yantao;  Kang Yaqing
收藏  |  浏览/下载:18/0  |  提交时间:2020/12/24
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/01
连氨基脲链的三氮唑并噻二唑类DOT1L抑制剂的设计、合成及活性 期刊论文
有机化学, 2020, 卷号: 40, 期号: 8, 页码: 2450
作者:  刘娜;  郭思岐;  刘俊芳;  陈彦韬;  徐晓明
收藏  |  浏览/下载:32/0  |  提交时间:2020/12/24
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:  Zhang, Li;  Chen, Yantao;  Liu, Na;  Li, Linjuan;  Xiao, Senhao
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
Convenient preparation of pinometostat and related 5 '-deoxy-5 '-amino adenosine derivatives as well as their activity against DOT1L 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 4, 页码: 415-417
作者:  Liu, Tongchao;  Ren, Huanming;  Li, Cong;  Chen, Guohua;  Cheng, Maosheng
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
The protective role of DOT1L in UV-induced melanomagenesis 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:  Zhu, Bo;  Chen, Shuyang;  Wang, Hongshen;  Yin, Chengqian;  Han, Changpeng
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05


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