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CORC

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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：84/0  |  提交时间：2021/11/04
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:  Chen, Li;  Lin, Zemin;  Liu, Yuting;  Cao, Shiqi;  Huang, Yueteng
收藏  |  浏览/下载：71/0  |  提交时间：2021/05/24
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yang, Fang-ming;  Fan, Di;  Yang, Xiao-qian;  Zhu, Feng-hua;  Shao, Mei-juan
收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：39/0  |  提交时间：2020/12/24
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Li, Heng;  Zuo, Jianping;  Tang, Wei
收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17 期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 443-452
作者:  Lin, Ze-Min;  Ma, Meng;  Li, Heng;  Qi, Qing;  Liu, Yu-Ting
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08
0.1%他克莫司滴眼液治疗难治性重度干眼疗效评价 学位论文
2017, 2016
杨舒
收藏  |  浏览/下载：6/0  |  提交时间：2017/06/20

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