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DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:  Chen, Li;  Lin, Zemin;  Liu, Yuting;  Cao, Shiqi;  Huang, Yueteng
收藏  |  浏览/下载:71/0  |  提交时间:2021/05/24
dz2002抑制角质细胞分泌趋化因子改善豚鼠银屑病样皮损 期刊论文
中国药理学通报, 2020, 卷号: 36, 期号: 4, 页码: 501
作者:  李迁;  祁青;  杨晓倩;  杨芳明;  林泽民
收藏  |  浏览/下载:38/0  |  提交时间:2020/07/01
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models 期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:  Zhang, Zongwang;  Wu, Yanwei;  Wu, Bing
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study 期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33
作者:  Jia, Weiwei;  Li, Jing;  Du, Feifei;  Sun, Yan;  Xu, Fang
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/01
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:  He, Shijun;  Liu, Xing;  Lin, Zemin;  Liu, Yuting;  Gu, Lei
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/01
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:  He,Shijun;  Liu,Xing;  Lin,Zemin;  Liu,Yuting;  Gu,Lei
收藏  |  浏览/下载:57/0  |  提交时间:2020/07/01
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study 期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1
作者:  Li, Chuan;  Olaleye, Olajide E.;  Chen, Danghui;  Tang, Wei;  Zuo, Jianping
收藏  |  浏览/下载:38/0  |  提交时间:2019/12/05
assaydevelopmentfordeterminationofdz2002anewreversiblesahhinhibitoranditsacidmetabolitedzainbloodandapplicationtoratpharmacokineticstudy 期刊论文
药物分析学报英文版, 2019, 卷号: 009, 期号: 001, 页码: 25
作者:  Weiwei Jia;  Jing Li;  Feifei Du;  Yan Sun;  Fang Xu
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/01
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17 期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 443-452
作者:  Lin, Ze-Min;  Ma, Meng;  Li, Heng;  Qi, Qing;  Liu, Yu-Ting
收藏  |  浏览/下载:51/0  |  提交时间:2019/01/08
可逆型的S-腺苷同型半胱氨酸水解酶抑制剂DZ2002对银屑病的治疗作用及机制研究 期刊论文
中国药理学与毒理学杂志, 2016, 卷号: 30, 期号: 10, 页码: 1089
作者:  林泽民;  马萌;  何世君;  唐炜;  左建平
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08


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