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CORC

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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：85/0  |  提交时间：2021/11/04
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Lu, Qiu-kai;  Fan, Chen;  Xiang, Cai-gui;  Wu, Bing;  Lu, Hui-min
收藏  |  浏览/下载：57/0  |  提交时间：2021/06/11
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：39/0  |  提交时间：2020/12/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：18/0  |  提交时间：2021/01/05
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:  Li, Heng;  Fan, Chen;  Feng, Chunlan;  Wu, Yanwei;  Lu, Huimin
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Rolipram, a PDE4 Inhibitor, Enhances the Inotropic Effect of Rat Heart by Activating SERCA2a 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 12
作者:  Huang, Huili;  Xie, Ming;  Gao, Li;  Zhang, Wenhui;  Zhu, Xiaojia
收藏  |  浏览/下载：56/0  |  提交时间：2019/06/20

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