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CORC

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Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:  Li, Heng;  Fan, Chen;  Feng, Chunlan;  Wu, Yanwei;  Lu, Huimin
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Li, Heng;  Zuo, Jianping;  Tang, Wei
收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Xie, Wei;  Ye, Yangliang;  Feng, Ying;  Xu, Tifei;  Huang, Suling
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08
A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 12, 页码: 1123-1128
作者:  Liu, Xin;  Tang, Gui-Hua;  Weng, Han-Zhuang;  Zhang, Jun-Sheng;  Xu, You-Kai
收藏  |  浏览/下载：41/0  |  提交时间：2019/04/22
Structure-based design and structure-activity relationships of 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors 期刊论文
2018, 卷号: 28, 期号: 7, 页码: 1188
作者:  Liao, Yixian[1,2];  Guo, Yiming[1];  Li, Sumei[3];  Wang, Lei[1];  Tang, Yongmei[1]
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/10
Design, synthesis and biological evaluation of 2,4-disubstituted oxazole derivatives as potential PDE4 inhibitors 期刊论文
2017, 卷号: 25, 期号: 6, 页码: 1852-1859
作者:  Li, Ya-Sheng;  Hu, De-Kun;  Zhao, Dong-Sheng;  Liu, Xing-Yu;  Jin, Hong-Wei
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/28
The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA 期刊论文
JOURNAL OF SEXUAL MEDICINE, 2013, 卷号: 10, 期号: 11, 页码: 2790-2797
作者:  Wang, Zhen;  Zhu, Difeng;  Yang, Xiaochun;  Li, Jianfeng;  Jiang, Xiangrui
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Multiple Pharmacophore Models Combined with Molecular Docking: A Reliable Way for Efficiently Identifying Novel PDE4 Inhibitors with High Structural Diversity 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2010, 卷号: 50, 期号: 4, 页码: 615-625
作者:  Chen, Zhi;  Tian, Guanghui;  Wang, Zhen;  Jiang, Hualiang;  Shen, Jingshan
收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08

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