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上海药物研究所 [35]
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期刊论文 [42]
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Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 18
作者:
Lin, Zemin
;
Liu, Yuting
;
Chen, Li
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
artemisinin analog
antiphospholipid syndrome
antiphospholipid syndrome nephropathy associated lupus nephritis
oxidative stress
inflammation
Nrf2
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:
Wang, Liang-Liang
;
Kong, Lingmei
;
Liu, Hui
;
Zhang, Yunqin
;
Zhang, Li
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/03/02
Artemisinin
Quinazoline
Hybridization
Colorectal cancer
Chemotherapy
Trace determination of mutagenic alkyl toluenesulfonate impurities via derivatization headspace-GC/MS in an active pharmaceutical ingredient of a candidate drug
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 155, 页码: 104-108
作者:
Liu, Xue-Wei
;
Zhang, Wen-Peng
;
Han, Hai-Yun
;
Sun, Ling
;
Chen, Dong-Ying
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  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
Mutagenic impurities
Alkyl toluenesulfonate
Derivatization
Headspace
GC/MS
Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 6, 页码: 885-896
作者:
Kang, Xue-jia
;
Wang, Hui-yuan
;
Peng, Hui-ge
;
Chen, Bin-fan
;
Zhang, Wen-yuan
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  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
human colon cancer
multidrug resistance
doxorubicin
dihydroartemisinin
combination therapy
tumor-targeted delivery
mannosylated liposome
mannose receptor
Artemisinin analogue SM934 attenuate collagen-induced arthritis by suppressing T follicular helper cells and T helper 17 cells
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Lin, Ze-Min
;
Yang, Xiao-Qian
;
Zhu, Feng-Hua
;
He, Shi-Jun
;
Tang, Wei
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  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2016, 卷号: 13, 期号: 3, 页码: 379-390
作者:
Wu, Yanwei
;
He, Shijun
;
Bai, Bingxin
;
Zhang, Luyao
;
Xue, Lu
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
B cell
plasma cell
SM934
systemic lupus erythematosus
Toll-like receptor
Development of artemisinin drugs in the treatment of autoimmune diseases
期刊论文
SCIENCE BULLETIN, 2016, 卷号: 61, 期号: 1, 页码: 37-41
作者:
Wu, Yanwei
;
Tang, Wei
;
Zuo, Jianping
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Artemisinin
Autoimmune disease
Anti-inflammatory
Immunosuppressive
SM934
therapeuticeffectsoftheartemisininanalogsm934onlupuspronemrllprmiceviainhibitionoftlrtriggeredbcellactivationandplasmacellformation
期刊论文
cellularmolecularimmunology, 2016, 卷号: 13, 期号: 3, 页码: 379
作者:
Wu Yanwei
;
He Shijun
;
Bai Bingxin
;
Zhang Luyao
;
Xue Lu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
B cell
plasma cell
SM934
systemic lupus erythematosus
Toll-like receptor
developmentofartemisinindrugsinthetreatmentofautoimmunediseases
期刊论文
sciencebulletin, 2016, 卷号: 61, 期号: 1, 页码: 37
作者:
Wu Yanwei
;
Wei Tang
;
Zuo Jianping
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
IMMUNOSUPPRESSIVE ACTIVITY
RHEUMATOID-ARTHRITIS
SIGNALING PATHWAY
DERIVATIVE SM905
DIHYDROARTEMISININ
ARTESUNATE
ACTIVATION
MECHANISM
ACIDS
MICE
Artemisinin
Autoimmune disease
Anti-inflammatory
Immunosuppressive
SM934
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