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CORC

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Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis 期刊论文
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 12
作者:  Liao, Min;  Dong, Qiongye;  Chen, Ruiqing;  Xu, Liqian;  Jiang, Yuxuan
收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/01
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：16/0  |  提交时间：2021/12/16
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 393
作者:  Chen, Cheng;  Wang, Li;  Li, Lili;  Wang, Aoli;  Huang, Tao
收藏  |  浏览/下载：26/0  |  提交时间：2020/11/26
Single-cell RNA sequencing of t(8;21) acute myeloid leukemia for risk prediction 期刊论文
ONCOLOGY REPORTS, 2020, 卷号: 43, 期号: 4, 页码: 1278-1288
作者:  Xiong, Qian;  Huang, Sai;  Li, Yong-Hui;  Lv, Na;  Lv, Chao
收藏  |  浏览/下载：57/0  |  提交时间：2020/12/10
The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01
Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores 期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 卷号: 23, 期号: 4, 页码: 295-303
作者:  Lu, Jing;  Zhang, YuHang;  Wang, ShaoPeng;  Bi, Yi;  Huang, Tao
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:  Wang, Jubo;  Li, Tinghan;  Zhao, Tengteng;  Wu, Tizhi;  Liu, Chuang
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01

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