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The role of hippocampus in memory reactivation: an implication for a therapeutic target against opioid use disorder
期刊论文
CURRENT ADDICTION REPORTS, 2022, 页码: 13
作者:
Dai, Zhong-hua
;
Xu, Xing
;
Chen, Wei-qi
;
Nie, Li-na
;
Liu, Ying
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/03/28
opioid withdrawal
memory reactivation
extinction
hippocampus
noradrenergic signaling
Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline
期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:
Yang, Fan
;
Ling, Shenglong
;
Zhou, Yingxin
;
Zhang, Yanan
;
Lv, Pei
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  |  
浏览/下载:41/0
  |  
提交时间:2021/11/01
cryo-EM structure
G protein-coupled receptor (GPCR)
partial and full agonists
conformational change
desensitization
Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 181, 页码: 6
作者:
Hu, Shuwei
;
Chen, Xiaoyu
;
Zhu, Mengying
;
Hu, Huifang
;
Zhou, Chen
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Deubiquitinase
USP20
DUSP domain
NMR
A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET
期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56
作者:
Shi, Pan
;
Zhang, Yanan
;
Lv, Pei
;
Fang, Wei
;
Ling, Shenglong
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  |  
浏览/下载:25/0
  |  
提交时间:2020/10/26
The Toxicity and Polymorphism of beta-Amyloid Oligomers
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 12, 页码: 19
作者:
Huang, Ya-ru
;
Liu, Rui-tian
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  |  
浏览/下载:21/0
  |  
提交时间:2020/09/22
beta-amyloid oligomers
Alzheimer's disease
polymorphism
toxicity
aggregation
Structural basis of ligand recognition and self-activation of orphan GPR52
期刊论文
NATURE, 2020, 页码: 21
作者:
Lin, Xi
;
Li, Mingyue
;
Wang, Niandong
;
Wu, Yiran
;
Luo, Zhipu
收藏
  |  
浏览/下载:162/0
  |  
提交时间:2020/07/01
The mechanoelectrical transducer channel is not required for regulation of cochlear blood flow during loud sound exposure in mice
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1
作者:
Burwood, George W. S.
;
Dziennis, Suzan
;
Wilson, Teresa
;
Foster, Sarah
;
Zhang, Yuan
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  |  
浏览/下载:28/0
  |  
提交时间:2020/12/16
OUTER HAIR-CELLS
LATERAL WALL
HEARING-LOSS
GUINEA-PIG
ADRENERGIC-INNERVATION
FLUID HOMEOSTASIS
STIMULATION
VELOCITY
GANGLION
EAR
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:
Wan, Fangping
;
Zhu, Yue
;
Hu, Hailin
;
Dai, Antao
;
Cai, Xiaoqing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Deep learning
Machine learning
Drug discovery
In silico drug screening
Compound-protein interaction prediction
Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Wu, Lingyan
;
Xia, Mingfeng
;
Duan, Yanan
;
Zhang, Lina
;
Jiang, Haowen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Rhodium(III)-Catalyzed [4+2] Annulation via C-H Activation: Synthesis of Multi-Substituted Naphthalenone Sulfoxonium Ylides
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 10, 页码: 17
作者:
Song, Xiaohan
;
Han, Xu
;
Zhang, Rui
;
Liu, Hong
;
Wang, Jiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
rhodium(III)
sulfoxonium ylides
naphthols
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