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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:73/0  |  提交时间:2021/08/17
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载:102/0  |  提交时间:2020/07/01
Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice 期刊论文
SCIENCE, 2020, 卷号: 367
作者:  Wu, Kun;  Wang, Shuansuo;  Song, Wenzhen;  Zhang, Jianqing;  Wang, Yun
收藏  |  浏览/下载:93/0  |  提交时间:2020/11/26
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Phase separation of Arabidopsis EMB1579 controls transcription, mRNA splicing, and development 期刊论文
PLOS BIOLOGY, 2020, 卷号: 18, 期号: 7
作者:  Zhang, Yiling;  Li, Zhankun;  Chen, Naizhi;  Huang, Yao;  Huang, Shanjin
收藏  |  浏览/下载:30/0  |  提交时间:2022/03/01
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465
作者:  Shi, Yi;  Ma, Hong-lei;  Zhuang, You-wen;  Wang, Xiao-xi;  Jiang, Yi
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/01
EZH2 inhibition suppresses bladder cancer cell growth and metastasis via the JAK2/STAT3 signaling pathway 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 1
作者:  Chen, Zhiyuan;  Du, Yang;  Liu, Xiuheng;  Chen, Hui;  Weng, Xiaodong
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/05
Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 6
作者:  Qu, Di;  Sun, Wei-Wei;  Li, Li;  Ma, Li;  Sun, Li
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Enhancer of zeste 2 polycomb repressive complex 2 subunit promotes sorafenib resistance of hepatocellular carcinoma though insulin-like growth factor 1 receptor 期刊论文
ANTI-CANCER DRUGS, 2019, 卷号: 30, 期号: 7, 页码: 677-684
作者:  Hu, Jing;  Zhang, Jing;  Sun, Feifei;  Qi, Mei;  Su, Peng
收藏  |  浏览/下载:24/0  |  提交时间:2019/12/11


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