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浏览/检索结果: 共62条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng 收藏  |  浏览/下载：50/0  |  提交时间：2022/01/18 Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452 作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui 收藏  |  浏览/下载：25/0  |  提交时间：2022/01/04 Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402 作者:  Jiao, Shang;  Guan, Dongliang;  Xu, Lili;  Liu, Bo;  Shi, Weiwei 收藏  |  浏览/下载：18/0  |  提交时间：2022/01/18 glycopeptide antibiotics  impurity  analytical method  process optimization and development   I-2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines 期刊论文 GREEN CHEMISTRY, 2021, 卷号: 23, 期号: 22, 页码: 9165-9171 作者:  Wei, Xiaohui;  Liang, Xuewu;  Li, Yazhou;  Liu, Qi;  Liu, Xuyi 收藏  |  浏览/下载：19/0  |  提交时间：2021/12/16 Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9 作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04 phosphoinositide 3-kinase (PI3K)  activation  inhibition  activity-dependent conformational changes   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16 Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing 收藏  |  浏览/下载：26/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation