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科研机构
上海药物研究所 [1158]
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期刊论文 [1130]
会议论文 [13]
学位论文 [13]
项目 [2]
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2021 [82]
2020 [105]
2019 [93]
2018 [126]
2017 [64]
2016 [74]
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Pharmacol... [11]
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Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases
期刊论文
FOOD CHEMISTRY, 2022, 卷号: 367, 页码: 14
作者:
Fu, Jia
;
Zhang, Le-Le
;
Li, Wei
;
Zhang, Yan
;
Zhang, Yamei
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
Functional foods
Metabolomics
Metabolites
Metabolic diseases
Food processing
Novel pectin-like polysaccharide from Panax notoginseng attenuates renal tubular cells fibrogenesis induced by TGF-beta
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 276, 页码: 12
作者:
Huang, Chunfan
;
Jing, Xiaoqi
;
Wu, Qianhu
;
Ding, Kan
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/12/16
Panax notoginseng
Polysaccharide
Renal fibrosis
Epithelial-mesenchymal transition
Pectin
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/01/18
Photoactivatable nanogenerators of reactive species for cancer therapy
期刊论文
BIOACTIVE MATERIALS, 2021, 卷号: 6, 期号: 12, 页码: 4301-4318
作者:
Zheng, Xiaohua
;
Jin, Yilan
;
Liu, Xiao
;
Liu, Tianqing
;
Wang, Weiqi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/16
Reactive oxygen species
Reactive nitrogen species
Alkyl radicals
Carbon monoxide
Phototherapy
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 卷号: 57, 期号: 91, 页码: 12098-12110
作者:
Tong, Pei-Hong
;
Zhu, Ling
;
Zang, Yi
;
Li, Jia
;
He, Xiao-Peng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
Discrete genetic loci in human gutBacteroides thetaiotaomicron confer pectin metabolism
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 272, 页码: 13
作者:
Li, Meixia
;
Li, Saijuan
;
Guo, Xiaozhen
;
Guo, Ciliang
;
Wang, Yeqin
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/11/04
Polysaccharide
Pectin
Human gut microbiota
Metabolism
Bacteroides
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