Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases

doi:10.1016/j.foodchem.2021.130697

	Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases
	Fu, Jia 1; Zhang, Le-Le 1; Li, Wei 1; Zhang, Yan 1; Zhang, Yamei 2,3; Liu, Fang 4; Zou, Liang 5
刊名	FOOD CHEMISTRY
	2022-01-15
卷号	367 页码:14
关键词	Functional foods Metabolomics Metabolites Metabolic diseases Food processing
ISSN号	0308-8146
DOI	10.1016/j.foodchem.2021.130697
通讯作者	Liu, Fang(lf86614@126.com) ; Zou, Liang(zouliangcdu@126.com)
英文摘要	Metabolomics is an important branch of systems biology, which can detect changes in the body's metabolism before and after the intervention of functional foods, identify effective metabolites, and predict the interventional effects and the mechanism. This review summarizes the latest research outcomes regarding interventional effects of functional foods on metabolic diseases via metabolomics analysis. Since metabolomics approaches are powerful strategies for revealing the changes in bioactive compounds of functional foods during processing and storage, we also discussed the effects of these parameters on functional food metabolites using metabolomics approaches. To date, a number of endogenous metabolites related to the metabolic diseases after functional foods intervention have been discovered. Unfortunately, the mechanisms of metabolic disease-related molecules are still unclear and require further studies. The combination of metabolomics with other omics technologies could further promote its ability to fully understand the precise biological processes of functional food intervention on metabolic diseases.
资助项目	Health and Family Planning Com-mission of Chengdu-Key Disciplines of Clinical Pharmacy
WOS关键词	HIGH-FAT DIET ; NF-KAPPA-B ; UNTARGETED METABOLOMICS ; AMPELOPSIS-GROSSEDENTATA ; COMPOSITIONAL CHANGES ; LIPID-ACCUMULATION ; OXIDATIVE STRESS ; GLYCEMIC CONTROL ; INDUCED OBESITY ; GANODERIC ACID
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000696986400008
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/297903]
专题	中国科学院上海药物研究所
通讯作者	Liu, Fang; Zou, Liang
作者单位	1.Chengdu Univ, Sch Basic Med Sci, Chengdu 610106, Peoples R China 2.Chengdu Univ, Clin Genet Lab, Affiliated Hosp, Chengdu 610081, Peoples R China 3.Chengdu Univ, Clin Med Coll, Chengdu 610081, Peoples R China 4.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 5.Chengdu Univ, Sichuan Engn & Technol Res Ctr Coarse Cereal Indu, Sch Food & Biol Engn, Minist Agr & Rural Affairs,Key Lab Coarse Cereal, Chengdu 610106, Peoples R China
推荐引用方式 GB/T 7714	Fu, Jia,Zhang, Le-Le,Li, Wei,et al. Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases[J]. FOOD CHEMISTRY,2022,367:14.
APA	Fu, Jia.,Zhang, Le-Le.,Li, Wei.,Zhang, Yan.,Zhang, Yamei.,...&Zou, Liang.(2022).Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases.FOOD CHEMISTRY,367,14.
MLA	Fu, Jia,et al."Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases".FOOD CHEMISTRY 367(2022):14.