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上海药物研究所 [8]
昆明植物研究所 [1]
高能物理研究所 [1]
湖南大学 [1]
湖南中医药大学 [1]
合肥物质科学研究院 [1]
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期刊论文 [13]
发表日期
2018 [13]
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Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma
期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:
Wang, Qi
;
Dai, Yang
;
Ji, Yinchun
;
Shi, Huanyu
;
Guo, Zuhao
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:
Wang, Jia
;
Gong, Grace Qun
;
Zhou, Yan
;
Lee, Woo-Jeong
;
Buchanan, Christina Maree
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
high throughput screening
PI3 kinase
PI3K alpha H1047R
inhibitors
molecular modeling
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:
Cheng, Zhi-Qiang
;
Zhu, Kong-Kai
;
Zhang, Juan
;
Song, Jia-Li
;
Muehlmann, Luis Alexandre
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  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Novel nor-monoterpenoid indole alkaloids inhibiting glioma stem cells from fruits of Alstonia scholaris
期刊论文
PHYTOMEDICINE, 2018, 卷号: 48, 页码: 170-178
作者:
Wang, Bei
;
Dai, Zhi
;
Yang, Xiong-Wu
;
Liu, Ya-Ping
;
Khan, Afsar
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2018/10/04
Glioma stem cells
Antitumor activity
Alstonia scholaris
Nor-monoterpenoid indole alkaloids
Enhancement of Glucose Utilization by Loesenerine through AMPK Activation in Myotubes
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 66, 期号: 9, 页码: 885-886
作者:
Wang, Luo-Na
;
Jiang, Hao-Wen
;
Li, Jin-Long
;
Li, Jing-Ya
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
loesenerine
spermidine alkaloid
AMP-activated protein kinase activation
glucose uptake
Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents
期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 7
作者:
Che, Jinxin
;
Wang, Zhilong
;
Sheng, Haichao
;
Huang, Feng
;
Dong, Xiaowu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
pharmacophore model
CXCR2
antagonists
anti-cancer metastasis
OsSND2, a NAC family transcription factor, is involved in secondary cell wall biosynthesis through regulating MYBs expression in rice
期刊论文
RICE, 2018, 卷号: 11, 期号: 无, 页码: 14
作者:
Ye, Yafeng
;
Wu, Kun
;
Chen, Jianfeng
;
Liu, Qian
;
Wu, Yuejin
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  |  
浏览/下载:63/0
  |  
提交时间:2019/08/23
Secondary cell wall (SCW)
Rice
Cellulose synthesis
Transcription factor (TF)
NAC
MYB
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483
作者:
Zhu, Kongkai
;
Jiang, Chengshi
;
Tao, Hongrui
;
Liu, Jingqiu
;
Zhang, Hua
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  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Resynthesis
Virtual screening
Molecular docking
Molecular dynamics simulation
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:
Song, Yakai
;
Li, Linjuan
;
Chen, Yantao
;
Liu, Jingqiu
;
Xiao, Senhao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
DOT1L
MLL-rearranged leukemia
AlphaLISA
HTS
Novel inhibitors
Screening of neuraminidase inhibitory activities of some medicinal plants traditionally used in Lingnan Chinese medicines
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
作者:
Liu, Jiawei
;
Zu, Mian
;
Chen, Kaotan
;
Gao, Li
;
Min, Huan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
A (H1N1) influenza virus
Neuraminidase inhibitor
Anti-influenza agents
Medicinal plant
Lingnan Chinese medicines
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