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浏览/检索结果: 共104条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位    发表日期：2020     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 12, 页码: 6242-6250 作者:  Abula, Amina;  Xu, Zhijian;  Zhu, Zhengdan;  Peng, Cheng;  Chen, Zhaoqiang 收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 Mechanism and optimization of supramolecular complexation-enhanced fluorescence spectroscopy for the determination of SN-38 in plasma and cells 期刊论文 LUMINESCENCE, 2020, 页码: 12 作者:  Zhao, Kena;  Guo, Tao;  Sun, Xian;  Xiong, Ting;  Ren, Xiaohong 收藏  |  浏览/下载：47/0  |  提交时间：2020/12/24 cyclodextrins  inclusion complex  pharmacokinetics  SN‐  38  spectrofluorimetric  transfer   A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions 期刊论文 SYNTHETIC COMMUNICATIONS, 2020, 页码: 10 作者:  Xue, Kangsheng;  Sun, Guoxiang;  Zhang, Yanzhi;  Chen, Xubing;  Zhou, Yang 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 Aldehyde  chalcone  Claisen-Schmidt reaction  ketone  PPh3  I2   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Synthesis and biological activity of C-7, C-9 and C-10 modified taxane analogues from 1-deoxybaccatin VI 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 21, 页码: 8 作者:  Xie, Chenghu;  Cui, Yongmei;  Li, Lanlan;  Zhang, Minmin;  Liu, Hongchun 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21 Paclitaxel  Taxane analogues  1-Deoxybaccatin VI  Synthesis  In vitro anticancer activity   Nostoc sphaeroids Kutz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 1734-1742 作者:  Li, Meixia;  Guo, Ciliang;  Wang, Yeqing;  Du, Zhenyun;  Chen, Sheng 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 Nostoc sphaeroids Kutz polysaccharide  Nostoc sphaeroids Kutz powder  16S ribosomal RNA gene sequencing  Core bacterial community   Dynamic structure model of polyelectrolyte complex based controlled-release matrix tablets visualized by synchrotron radiation micro-computed tomography 期刊论文 MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020, 卷号: 116, 页码: 9 作者:  Yin, Xianzhen;  Li, Liang;  Gu, Xiangqin;  Wang, Huimin;  Wu, Li 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 Chitosan-carrageenan matrix  Sustained release  Synchrotron radiation X-ray micro-tomography  Microstructure  Hydration dynamic   A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115 作者:  Bian, Youcheng;  Zeng, Hui;  Tao, Hong;  Huang, Lulin;  Du, Zhenyun 收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24 Polygala tenuifolia  Pectin  Pancreatic cancer  Apoptosis  Autophagy   Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408 作者:  Liu, Jian-Guo;  Zhao, Danfeng;  Gong, Qi;  Bao, Fengxia;  Chen, Wen-Wen 收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24 Glycogen synthase kinase-3  bisindole-substituted aminopyrazoles  Alzheimer's disease  oxidative neurotoxicity  microglial inflammation   A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 161, 页码: 35-43 作者:  Zeng, Hui;  Li, Piaopiao;  Zhou, Lishuang;  Ding, Kan 收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21 Polygala tenuifolia  Pectin  Polysaccharide  A beta(42) Alzheimer's disease