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科研机构
西北高原生物研究所 [19]
上海药物研究所 [14]
新疆理化技术研究所 [4]
上海营养与健康研究所 [3]
中国医学科学院 北京... [3]
中国科学院大学 [2]
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期刊论文 [47]
学位论文 [8]
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Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/01
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Succinyl rotundic acid inhibits growth and promotes apoptosis in the HeLa cervical cancer cell line
期刊论文
Materials Express, 2020, 卷号: 10, 期号: 4, 页码: 571-577
作者:
Y. F. He,J. M. Sun,M. L. Nang,X. Wang,H. Lin,G. F. Lv,Y. Li,M. H. Duan and H. B. Ye
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  |  
浏览/下载:4/0
  |  
提交时间:2021/07/06
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
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  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Impact of hyperlipidemia as a coexisting factor on the prognosis of idiopathic sudden sensorineural hearing loss: A propensity score matching analysis
期刊论文
Clinical Otolaryngology, 2019
作者:
Chen C.
;
Wang M.
;
Wang H.
;
Xiong W.
;
Dai Q.
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
hyperlipidezmia
lipid-lowering therapy
propensity score
sudden hearing loss
treatment outcome
Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin beta 3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 265-278
作者:
Jin, Hongyue
;
He, Yang
;
Zhao, Pengfei
;
Hu, Ying
;
Tao, Jin
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Epithelial-mesenchymal transition
cholesterol metabolism
tumor-associated macrophages
simvastatin
drug resistance
legumain
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Proteomics analysis reveals a potential new target protein for the lipid-lowering effect of Berberine8998
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1473-1482
作者:
Yu, Cheng-yin
;
Liu, Gang-yi
;
Liu, Xiao-hui
;
Gui, Yu-zhou
;
Liu, Hai-ming
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Flavonoid Glycosides from Fenugreek Seeds Regulate Glycolipid Metabolism by Improving Mitochondria! Function in 3T3-L1 Adipocytes in Vitro
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018
Luan, Guangxiang
;
Wang, Yuwei
;
Wang, Zhenhua
;
Zhou, Wenna
;
Hu, Na
;
Li, Gang
;
Wang, Honglun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/06/14
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