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CORC

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Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01
Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30
作者:  Jia, Xiuwen;  Li, Pinyi;  Liu, Xiaoyan;  Lin, Jiafu;  Chu, Yiwen
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia 期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:  Wu Chenglin;  Xi Cong;  Tong Junhua;  Zhao Jing;  Jiang Hualiang
收藏  |  浏览/下载：52/0  |  提交时间：2020/07/01
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:  Guo, Diliang;  Li, Jing;  Lin, Henry;  Zhou, Yu;  Chen, Ying
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D-1, D-2 and serotonin 5-HT1A multiple action profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 21, 页码: 5838-5846
作者:  Li, Zeng;  Huang, Jiye;  Sun, Haifeng;  Zhou, Shengbin;  Guo, Lin
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D-1, D-2 and serotonin 5-HT1A multi-action profile 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 4, 页码: 856-868
作者:  Sun, Haifeng;  Zhu, Liyuan;  Yang, Huicui;  Qian, Wangke;  Guo, Lin
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: Selective inhibitors of dopamine D-1 receptor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 15, 页码: 4862-4871
作者:  Qian, Wangke;  Lu, Weijian;  Sun, Haifeng;  Li, Zeng;  Zhu, Liyuan
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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