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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Radiation dose escalation for locally advanced nasopharyngeal carcinoma patients with local and/or regional residual lesions after standard chemoradiotherapy: a non-randomized, observational study
期刊论文
RADIATION ONCOLOGY, 2022, 卷号: 17
作者:
Jin, Ting
;
Liu, Nan-Fang
;
Jin, Qi-Feng
;
Hua, Yong-Hong
;
Chen, Xiao-Zhong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/23
Nasopharyngeal carcinoma
Boost
Radiotherapy
Residual lesion
Chemotherapy
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119
作者:
Zhang, Pengge
;
Zhou, Zhixuan
;
Long, Wen
;
Yan, Yuping
;
Li, Youshan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
self-assembly
supramolecular coordination complex
combination chemotherapy
targeted cancer therapy
drug delivery
Assembled Fe3O4 nanoparticles on Zn-Al LDH nanosheets as a biocompatible drug delivery vehicle for pH-responsive drug release and enhanced anticancer activity
期刊论文
APPLIED CLAY SCIENCE, 2022, 卷号: 228
作者:
Chai, JH
;
Ma, YY
;
Guo, TL
;
He, Y
;
Wang, GS
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  |  
浏览/下载:10/0
  |  
提交时间:2022/12/02
Photoactivatable nanogenerators of reactive species for cancer therapy
期刊论文
BIOACTIVE MATERIALS, 2021, 卷号: 6, 期号: 12, 页码: 4301-4318
作者:
Zheng, Xiaohua
;
Jin, Yilan
;
Liu, Xiao
;
Liu, Tianqing
;
Wang, Weiqi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/16
Reactive oxygen species
Reactive nitrogen species
Alkyl radicals
Carbon monoxide
Phototherapy
Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021, 页码: 25
作者:
Xu, Xiaoxuan
;
Wu, Yao
;
Qian, Xindi
;
Wang, Yuqi
;
Wang, Jiaoying
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/12/16
cancer therapy
drug delivery
extracellular matrix
nanomedicine
tumor penetration
RNA-binding protein 39: a promising therapeutic target for cancer
期刊论文
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 9
作者:
Xu, Caipeng
;
Chen, Xiaohua
;
Zhang, Xuetian
;
Zhao, Dapeng
;
Dou, Zhihui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/08
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:
Zheng, Mengmeng
;
Li, Chunpu
;
Zhou, Mi
;
Jia, Ru
;
Cai, Gang
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  |  
浏览/下载:60/0
  |  
提交时间:2021/11/04
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