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上海药物研究所 [6]
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期刊论文 [14]
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Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections
期刊论文
ACS INFECTIOUS DISEASES, 2018, 卷号: 4, 期号: 3, 页码: 208-217
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Chen, Feifei
;
Mao, Fei
;
Wei, Hanwen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Staphylococcus aureus
diapophytoene desaturase
methicillin-resistant Staphylococcus aureus
hERG safety
Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 233-237
作者:
Ni, Shuaishuai
;
Li, Baoli
;
Chen, Feifei
;
Wei, Hanwen
;
Mao, Fei
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Virulence factor
pigment
multidrug resistant MRSA
CrtN inhibitor
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 235-251
作者:
Wei, Hanwen
;
Mao, Fei
;
Ni, Shuaishuai
;
Chen, Feifei
;
Li, Baoli
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
CrtN inhibitor
STX biosynthesis
Pigment inhibitory activity
Resistant S. aureus
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 224-250
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Mao, Fei
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19, 页码: 8145-8159
作者:
Ni, Shuaishuai
;
Wei, Hanwen
;
Li, Baoli
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Expansion of chemical space for natural products by uncommon P450 reactions
期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1061-1089
作者:
Zhang, Xingwang
;
Li, Shengying
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浏览/下载:35/0
  |  
提交时间:2017/12/04
Genome-wide identification and characterization of macrolide glycosyltransferases from a marine-derived Bacillus strain and their phylogenetic distribution
期刊论文
ENVIRONMENTAL MICROBIOLOGY, 2016, 卷号: 18, 期号: 12, 页码: 4770-4781
作者:
Liu, Yang
;
Qin, Wen
;
Liu, Quanquan
;
Zhang, Jun
;
Li, Huayue
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  |  
浏览/下载:8/0
  |  
提交时间:2019/08/19
Uncovering a Glycosyltransferase Provides Insights into the Glycosylation Step during Macrolactin and Bacillaene Biosynthesis
期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 期号: 18, 页码: 2747-2753
作者:
Qin, Wen
;
Liu, Yang
;
Ren, Pengfei
;
Zhang, Jun
;
Li, Huayue
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/08/19
bacillaenes (BAEs)
Bacillus marinus
biosynthesis
glycosylation
glycosyltransferases
macrolactins
Direct proteomic mapping of Streptomyces roseosporus NRRL 11379 with precursor and insights into daptomycin biosynthesis
期刊论文
http://dx.doi.org/10.1016/j.jbiosc.2013.10.021, 2014
Ye, Chiming
;
Ng, I-Son
;
Jing, Keju
;
Lu, Yinghua
;
敬科举
;
卢英华
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/07/22
TOP-DOWN
MASS-SPECTROMETRY
BOTTOM-UP
COELICOLOR
OPTIMIZATION
VANCOMYCIN
GROWTH
RNA
Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis
期刊论文
BMC GENOMICS, 2014, 卷号: 15
作者:
Xu, Li
;
Huang, He
;
Wei, Wei
;
Zhong, Yi
;
Tang, Biao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Amycolatopsis orientalis
Complete genome sequencing
Molecular taxonomic characteristics
Vancomycin biosynthesis
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