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大连化学物理研究所 [3]
西安交通大学 [2]
上海药物研究所 [2]
上海有机化学研究所 [2]
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兰州大学 [1]
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期刊论文 [16]
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Rolipram, a PDE4 Inhibitor, Enhances the Inotropic Effect of Rat Heart by Activating SERCA2a
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 12
作者:
Huang, Huili
;
Xie, Ming
;
Gao, Li
;
Zhang, Wenhui
;
Zhu, Xiaojia
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/06/20
PDE4
rolipram
P-V loop
Ca2+ transient
SERCA2a
Rolipram, a pde4 inhibitor, enhances the inotropic effect of rat heart by activating serca2a
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 12
作者:
Huang, Huili
;
Xie, Ming
;
Gao, Li
;
Zhang, Wenhui
;
Zhu, Xiaojia
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/05/08
Pde4
Rolipram
P-v loop
Ca2+ transient
Serca2a
Comparison of the Full-Length and 152~528 Truncate of Human Cyclic Nucleotide Phosphodiesterase 4B2 for the Characterization of Inhibitors.
期刊论文
Combinatorial chemistry & high throughput screening, 2019
作者:
Xiang Zhang
;
Shu He
;
Xiaolei Hu
;
Jing Wu
;
Xinpeng Li
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/17
SUMO tag
human cyclic nucleotide phosphodiesterase 4B
inflammator
inhibitor
rolipram
truncate
The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, 卷号: 38, 期号: [db:dc_citation_issue], 页码: 1433-1442
作者:
Guo, Chi-Hua
;
Bai, Lu
;
Wu, Huang-Hui
;
Yang, Jing
;
Cai, Guo-Hong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
chemokine (C-C motif) ligand 2 pathway pathway
c-Jun N-terminal kinase
neuroglia
rolipram
analgesic
bone cancer pain
Rolipram stimulates angiogenesis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2016, 卷号: 11, 期号: [db:dc_citation_issue], 页码: 1005-1010
作者:
Hu, Shouye
;
Cao, Qingwen
;
Xu, Peng
;
Ji, Wenchen
;
Wang, Gang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
cAMP/cAMP-responsive element binding protein pathway
neuronal apoptosis
angiogenesis
rolipram
rat
Inhibition of phosphodiesterase-4 reverses the cognitive dysfunction and oxidative stress induced by A beta 25-35 in rats (SCI收录)
期刊论文
METABOLIC BRAIN DISEASE, 2016, 卷号: 31, 页码: 779-791
作者:
Zhuo, Yeye[1,2]
;
Guo, Haibiao[1]
;
Cheng, Yufang[1]
;
Wang, Chuang[3]
;
Wang, Canmao[4]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/24
Rolipram
Phosphodiesterase-4
Oxidative stress
Memory
beta-amyloid
Phosphodiesterase 3/4 Inhibitor Zardaverine Exhibits Potent and Selective Antitumor Activity against Hepatocellular Carcinoma Both In Vitro and In Vivo Independently of Phosphodiesterase Inhibition
期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3
作者:
Sun, Liping
;
Quan, Haitian
;
Xie, Chengying
;
Wang, Lei
;
Hu, Youhong
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  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Rolipram promotes remyelination possibly via MEK-ERK signal pathway in cuprizone-induced demyelination mouse
期刊论文
EXPERIMENTAL NEUROLOGY, 2012, 卷号: 237, 期号: 2
作者:
Sun, Xiaojia
;
Liu, Yuting
;
Liu, Boyang
;
Xiao, Zhicheng
;
Zhang, Liming
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
Rolipram
PDE4 inhibitor
Demyelination
Remyelination
Oligodendrocyte precursor cell
Cuprizone
MAPK
Regio- and Enantioselective Palladium-Catalyzed Allylic Alkylation of Nitromethane with Monosubstituted Allyl Substrates: Synthesis of (R)-Rolipram and (R)-Baclofen
期刊论文
J. Org. Chem., 2012, 卷号: 77, 期号: 20, 页码: 8980-8985
杨晓菲
;
丁昌华
;
李小惠
;
黄建强
;
侯雪龙
;
戴立信
;
王贫杰
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2013/08/22
Asymmetric Synthesis of beta-Substituted gamma-Lactams via Rhodium/Diene-Catalyzed 1,4-Additions: Application to the Synthesis of (R)-Baclofen and (R)-Rolipram
期刊论文
ORGANIC LETTERS, 2011, 卷号: 13, 期号: 4
-
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浏览/下载:2/0
  |  
提交时间:2014/12/05
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