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北京大学 [9]
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上海药物研究所 [2]
复旦大学上海医学院 [2]
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期刊论文 [23]
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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing
期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:
Zhang, Mingkun
;
Zheng, Zhi
;
Zhou, Jin
;
Ding, Qihan
;
Long, Mian
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/25
Nanopore sensing
Atomic force microscopy (AFM)
Protein allostery
Steered molecular dynamics (SMD)
Spheroid approximation
Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing
期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:
Zhang MK(张明焜)
;
Zheng Z(郑植)
;
Zhou J(周瑾)
;
Ding QH(丁奇寒)
;
Long M(龙勉)
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/25
Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing
期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:
Zhang MK(张明焜)
;
Zheng Z(郑植)
;
Zhou J(周瑾)
;
Ding QH(丁奇寒)
;
Long M(龙勉)
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/25
The allosteric gating mechanism of the MthK channel
期刊论文
NATIONAL SCIENCE REVIEW, 2022, 卷号: 9
作者:
Guan, Fenghui
;
Li, Tianyu
;
Dong, Wei
;
Guo, Rui
;
Chai, Hao
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  |  
浏览/下载:10/0
  |  
提交时间:2022/12/23
ion channel
allosteric gating mechanism
protein structural data analysis
The endoplasmic reticulum (ER) chaperones BiP and Grp94 selectively associate when BiP is in the ADP conformation
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 16
作者:
Sun, Ming
;
Kotler, Judy L. M.
;
Liu, Shanshan
;
Street, Timothy O.
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
heat shock protein 90 (Hsp90)
chaperone
nucleotide
fluorescence resonance energy transfer (FRET)
fluorescence anisotropy
nuclear magnetic resonance (NMR)
allostery
BiP
Grp94
structural dynamics
Allostery in Drug Development
期刊论文
PROTEIN ALLOSTERY IN DRUG DISCOVERY, 2019, 卷号: 1163, 页码: 1-23
作者:
Cheng, Xi
;
Jiang, Hualiang
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  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Allosteric perturbation
Biased agonists
Conformational changes
Protein dynamics
Rational drug design
Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018, 卷号: 1862, 期号: 7, 页码: 1667-1679
作者:
Liang, Zhongjie
;
Hu, Junchi
;
Yan, Wenying
;
Jiang, Hualiang
;
Hu, Guang
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  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Conformational dynamics
Allosteric communication
Elastic network models, network theory, coevolution analysis
Structural insights into ca2+-activated long-range allosteric channel gating of ryr1
期刊论文
Cell research, 2016, 卷号: 26, 期号: 9, 页码: 977-994
作者:
Wei, Risheng
;
Wang, Xue
;
Zhang, Yan
;
Mukherjee, Saptarshi
;
Zhang, Lei
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  |  
浏览/下载:56/0
  |  
提交时间:2019/05/09
Ca2+ activation
Cryo-electron microscopy
Channel gating
Ion selectivity
Long-range allostery
Ryanodine receptor
Single-particle analysis
Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks
其他
2016-01-01
Chen, Yin-ying
;
Yu, Ya-nan
;
Zhang, Ying-ying
;
Li, Bing
;
Liu, Jun
;
Li, Dong-feng
;
Wu, Ping
;
Wang, Jie
;
Wang, Zhong
;
Wang, Yong-yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/04
PROTEIN-INTERACTION NETWORKS
DRUG DISCOVERY
CEREBRAL-ISCHEMIA
MOUSE HIPPOCAMPUS
PATHWAYS
ALLOSTERY
EXPRESSION
PREDICTION
COMPLEXES
OCCLUSION
Allostery in molecular self-assemblies: metal ions triggered self-assembly and emissions of terthiophene
期刊论文
CHEMICAL COMMUNICATIONS, 2016
Liu, Shuai
;
Zhao, Li
;
Xiao, Yunlong
;
Huang, Tian
;
Li, Jie
;
Huang, Jianbin
;
Yan, Yun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
DNA
FLUORESCENCE
COMPLEX
OLIGOTHIOPHENES
RECEPTORS
BEHAVIOR
NANOTUBE
BINDING
PROTEIN
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