×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [81]
北京大学 [19]
大连化学物理研究所 [15]
过程工程研究所 [14]
上海生物化学与细胞生... [9]
山东大学 [8]
更多...
内容类型
期刊论文 [239]
学位论文 [6]
会议论文 [3]
其他 [1]
无文献类型 [1]
发表日期
2022 [4]
2021 [6]
2020 [19]
2019 [25]
2018 [21]
2017 [12]
更多...
学科主题
Pharmacolo... [7]
Biochemist... [5]
物理化学 [5]
Chemistry [3]
Chemistry;... [2]
Biochemist... [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共250条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:
Li N(李宁)
;
Zhang XY(张晓宇)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Shu XY(舒芯钰)
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/10/23
Liver tissue stiffness
Shear stress
Hydrostatic pressure
Hepatocytes
Hepatocellular carcinoma
Liver sinusoidal endothelial cells
Hepatic stellate cells
Mechanotransduction pathways
Mechanomedicine
Drug design and delivery
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:
Sun, Lei
;
Zheng, Zhi-Ming
;
Shao, Chang-Sheng
;
Zhang, Zhi-Yong
;
Li, Ming-Wei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/22
glucagon-like peptide-1
GLP-1 receptor agonist
functional protein design
molecular dynamics simulation
long-acting antihyperglycemic
Acetylcholinesterase Activity Monitoring and Natural Antineurological Disease Drug Screening via Rational Design of Deep Eutectic Solvents and CeO2‑Co(OH)2 Nanosheets
期刊论文
Analytical Chemistry, 2022, 期号: 94, 页码: 5970−5979
作者:
Yun Liu
;
Xin Wei
;
Jia Chen
;
Yong-Liang Yu
;
Jian-Hua Wang
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/04/25
Mechanism investigation for ultra-efficient photocatalytic water disinfection based on rational design of indirect Z-scheme heterojunction black phosphorus QDs/Cu2O nanoparticles
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 424
作者:
Luo, SJ
;
Liu, RX
;
Zhang, XX
;
Chen, R
;
Yan, MM
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/02
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/12/16
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Integrating DNA Nanotechnology with Aptamers for Biological and Biomedical Applications
期刊论文
MATTER, 2021, 卷号: 4
作者:
Huang, Zike
;
Qiu, Liping
;
Zhang, Tao
;
Tan, Weihong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/17
Dynamic folding modulation generates FGF21 variant against diabetes
期刊论文
EMBO REPORTS, 2021, 卷号: 22
作者:
Zhu, Lei
;
Zhao, Hongxin
;
Liu, Juanjuan
;
Cai, Hao
;
Wu, Bo
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/08/30
anti‐
diabetes
disulfide bond mutation
FGF21
folding dynamics
NMR
Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15
作者:
Yu, Qing
;
Sun, Yi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/03/15
anti-cancer drug
cullin-RING E3 ligases
natural product
high-throughput screen
neddylation
small-molecule inhibitors
Rational design of non-toxic GOx-based biocatalytic nanoreactor for multimodal synergistic therapy and tumor metastasis suppression
期刊论文
THERANOSTICS, 2021, 卷号: 11
作者:
Hang, Lifeng
;
Zhang, Tao
;
Wen, Hua
;
Li, Meng
;
Liang, Lianbao
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
Glucose oxidase
tirapazamine
metal-organic framework
biocatalytic nanoreactor
starvation therapy
©版权所有 ©2017 CSpace - Powered by
CSpace