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上海药物研究所 [11]
自动化研究所 [4]
过程工程研究所 [2]
上海大学 [1]
华中师范大学 [1]
湖南大学 [1]
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期刊论文 [22]
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2021 [2]
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Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13
作者:
Du, Yang
;
Liu, Ye
;
Wang, Di
;
Bai, Hua
;
Wang, Zhijie
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/06
immunotherapy
immunogenicity
vaccine
tumor microenvironment
lymphocytes
tumor infiltrating
macrophages
Molecular Dynamics Simulations Reveal the Modulated Mechanism of STING Conformation
期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2021, 页码: 15
作者:
Chen, Li
;
Zhao, Shuang
;
Zhu, Yanyan
;
Liu, Yongsheng
;
Li, Huiyu
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
STING
Small molecule
Binding site
Modulated mechanism
Molecular dynamics simulation
pi-pi stacking interaction
PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16
作者:
Sun, Pu
;
Zhang, Xi
;
Wang, Rong-Jing
;
Ma, Qing-Yang
;
Xu, Lan
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
tumor microenvironment
immunomodulation
immunologic memory
lymphocytes
tumor-infiltrating
macrophages
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Pu
;
Meng, Ling-hua
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  |  
浏览/下载:39/0
  |  
提交时间:2020/12/21
phosphoinositide 3-kinase (PI3K)
PI3K inhibitors
tumor microenvironment
immune cells
immunotherapy
Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer
期刊论文
NANO LETTERS, 2020, 卷号: 20, 期号: 6, 页码: 4393-4402
作者:
Zhou, Lei
;
Hou, Bo
;
Wang, Dangge
;
Sun, Fang
;
Song, Rundi
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  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Polymeric prodrug
Neoantigen
Adaptive immune response
Personalized immunotherapy
Nanoparticles
Generalizable, Reproducible, and Neuroscientifically Interpretable Imaging Biomarkers for Alzheimer's Disease
期刊论文
ADVANCED SCIENCE, 2020, 页码: 12
作者:
Jin, Dan
;
Zhou, Bo
;
Han, Ying
;
Ren, Jiaji
;
Han, Tong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/20
Alzheimer's disease
computer-aided diagnosis
neurobiological basis
neuroscientifically interpretable biomarkers
structural magnetic resonance imaging
Generalizable, Reproducible, and Neuroscientifically Interpretable Imaging Biomarkers for Alzheimer's Disease
期刊论文
ADVANCED SCIENCE, 2020, 页码: 12
作者:
Jin, Dan
;
Zhou, Bo
;
Han, Ying
;
Ren, Jiaji
;
Han, Tong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/20
Alzheimer's disease
computer-aided diagnosis
neurobiological basis
neuroscientifically interpretable biomarkers
structural magnetic resonance imaging
Engineering autologous tumor cell vaccine to locally mobilize antitumor immunity in tumor surgical bed
期刊论文
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 25, 页码: 13
作者:
Fang, Lei
;
Zhao, Zitong
;
Wang, Jue
;
Zhang, Pengcheng
;
Ding, Yaping
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  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Engineered hepatitis B core virus-like particle carrier for precise and personalized Alzheimer's disease vaccine preparation via fixed-point coupling
期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 19, 页码: 16
作者:
Ji, Mei
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Lu, Shuai
;
Zhang, Ling-xiao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/22
Alzheimer's disease
Virus-like particles (VLPs)
B cell epitope peptide
SpyCatcher/SpyTag
Th2-type immune response
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
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