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上海药物研究所 [18]
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兰州大学 [2]
大连化学物理研究所 [2]
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华南理工大学 [2]
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期刊论文 [44]
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Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:
Liao Xiaoying
;
Deng Qiangqiang
;
Han Li
;
Wu Zhitao
;
Peng Zhaoliang
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drugdrug interaction
pharmacokinetics
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
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  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 卷号: 853
作者:
Lin, Hua
;
Tu, Caixia
;
Niu, Yanfen
;
Li, Fashuang
;
Yuan, Lixian
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  |  
浏览/下载:21/0
  |  
提交时间:2019/12/04
Norathyriol
Hyperuricaemia
Uricosuric effect
Renal urate transporter
Organic anion transporter 1
Xanthine oxidase
Effects on Expression of Hepatic Phase-1 and Phase-2 Metabolism and Transporter Genes by Swertia mussotii Extract, A Hepatoprotective Herb from Tibetan Traditional Medicine
期刊论文
INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGY, 2019, 卷号: 21, 期号: 5
作者:
Yang, Hongxia
;
Xiao, Yuancan
;
Li, Cen
;
Gao, Tingting
;
Wei, Lixin
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  |  
浏览/下载:55/0
  |  
提交时间:2019/11/26
Tibetan traditional medicine
Swertia mussotii
Cytochrome P450
Hepatic transporters
New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3
期刊论文
Natural Product Research, 2019, 卷号: Vol.33 No.23, 页码: 3409-3416
作者:
Pang, X.a,b
;
Wang, L.-M.a,b
;
Zhang, Y.-C.c
;
Kang, L.-P.d
;
Yu, H.-S.a
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浏览/下载:6/0
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提交时间:2019/11/21
Leguminosae
Senna obtusifolia
Cassia obtusifolia
human organic anion transporter
OAT
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
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  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
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  |  
浏览/下载:47/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats
期刊论文
Toxicology Letters, 2018, 卷号: Vol.295, 页码: 195-204
作者:
Shijie Wen
;
Changyuan Wang
;
Xiaokui Huo
;
Qiang Meng
;
Zhihao Liu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
Vancomycin
JBP485
Nephrotoxicity
Transporter
Endogenous toxins
Liver Receptor Homolog-1 Regulates Organic Anion Transporter 2 and Docetaxel Pharmacokinetics
期刊论文
2018, 卷号: 46, 期号: 7, 页码: 980
作者:
Yu, Fangjun[1,2]
;
Zhang, Tianpeng[1]
;
Guo, Lianxia[1]
;
Wu, Baojian[1,2]
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
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