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Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Systematic investigation on the anti-rheumatoid arthritis material basis and mechanism of Juan Bi Tang. Part 1: Integrating metabolic profiles and network pharmacology
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202, 页码: 11
作者:
Li, Jiajia
;
Li, Lei
;
Wang, Yangyang
;
Zhao, Yuxuan
;
Hu, Pei
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
Juanbi-Tang (JBT)
Rheumatoid arthritis (RA)
Metabolites
Mass
Network pharmacology
Molecular docking
Identification of the absorbed ingredients and metabolites in rats after an intravenous administration of Tanreqing injection using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Xie, Like
;
Wang, Yangyang
;
Yin, Hao
;
Li, Jiajia
;
Xu, Zhou
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/05/24
COVID‐
19
metabolic profiles
quadrupole time‐
of‐
flight mass spectrometry
Tanreqing injection
traditional Chinese medicine
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15
作者:
Liu, Huan
;
Sun, Zhaolin
;
Tian, Xiaoting
;
Feng, Qin
;
Guo, Ziqiong
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
HPLC-Q-TOF
intestinal bacteria
liver
metabolism
Qushi Huayu Fang
Per- and polyfluoroalkyl substances display structure-dependent inhibition towards UDP-glucuronosyltransferases
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
作者:
Liu, Yong-Zhe
;
Zhang, Zhi-Peng
;
Fu, Zhi-Wei
;
Yang, Kun
;
Ding, Ning
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Per- and polyfluoroalkyl substances (PFASs)
UDP-Glucuronosyltransferases (UGTs)
Half inhibition concentration (IC50)
Inhibition type
Inhibition kinetic parameters (Ki)
In vitro-in vivo extrapolation (IVIVE)
Rapid structure identification of nineteen metabolites of ondansetron in human urine using LC/MSn
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 页码: 7
作者:
Duan, Mingyu
;
Qin, Li
;
Zhong, Dafang
;
Zhang, Peng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
human metabolism
LC
MSn
metabolic pathways
ondansetron
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 1: Metabolic profiles from the liver-centric perspective
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 237, 页码: 81-91
作者:
Liu, Huan
;
Chen, Mingcang
;
Yin, Hao
;
Hu, Pei
;
Wang, Yangyang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Yin-chen-hao tang
Liver
Metabolites
Liver injury
HPLC-Q-TOF
Carbon tetrachloride
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:
Geng, Chang-An
;
Yang, Tong-Hua
;
Huang, Xiao-Yan
;
Ma, Yun-Bao
;
Zhang, Xue-Mei
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/06/24
Uncaria rhynchophylla
Catechin
Melatonin receptors
Metabolites
Antidepressant activity
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