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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection 期刊论文 CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8 作者:  Zhang, Shihai;  Pei, Rongjuan;  Li, Meixia;  Su, Haixia;  Sun, Hao 收藏  |  浏览/下载：71/0  |  提交时间：2021/12/16 COVID-19  SARS-CoV-2  Angiotensin converting enzyme 2 (ACE2)  3CL protease  Ecklonia kurome Okam  Polysaccharide   Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing 收藏  |  浏览/下载：25/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia 收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17 Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20 作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 PDE4 inhibitors  Tetrahydroisoquinoline  Antipsoriasis   What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design 期刊论文 MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34 作者:  Xiong, Muya;  Su, Haixia;  Zhao, Wenfeng;  Xie, Hang;  Shao, Qiang 收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 3C-like protease  binding modes  coronavirus  inhibitors  structure and function   USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文 FEBS JOURNAL, 2020, 页码: 18 作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying 收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24 colorectal cancer  HDX-MS  inhibitor  USP25  USP28  Vismodegib   Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文 SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+ 作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya 收藏  |  浏览/下载：58/0  |  提交时间：2020/12/24 Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文 SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+ 作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian 收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4090-4106 作者:  Su, Haixia;  Zou, Yi;  Chen, Guofeng;  Dou, Huixia;  Xie, Hang 收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01