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Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2
作者:  Cui, Ying-Jie;  Tang, Long-Qian;  Zhang, Cheng-Mei;  Liu, Zhao-Peng
收藏  |  浏览/下载:122/0  |  提交时间:2019/12/11
Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties 期刊论文
Investigational New Drugs, 2019
作者:  Wu J.-D.;  Cui Y.-J.;  Zhou Y.-G.;  Tang L.-Q.;  Zhang C.-M.
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/11
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
European Journal of Medicinal Chemistry, 2019, 页码: 73-86
作者:  Zhao W.;  He L.;  Xiang T.-L.;  Tang Y.-J.
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 927-933
作者:  Wu, Xingkang;  Shen, Yuemao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
Design, synthesis, biological evaluation and molecular modeling study of novel macrocyclic bisbibenzyl analogues as antitubulin agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 129, 页码: 186-208
作者:  Sun, Bin;  Li, Lin;  Hu, Qing-wen;  Zheng, Hong-bo;  Tang, Hui
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/12
A new method to effectively and rapidly generate neurons from SH-SY5Y cells 期刊论文
NEUROSCIENCE LETTERS, 2016, 卷号: 610, 页码: 43-47
作者:  Yang, HongNa;  Wang, Jing;  Sun, JinHua;  Liu, XiaoDun;  Duan, Wei-Ming
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/16
Design, synthesis and biological evaluation of novel macrocyclic bisbibenzyl analogues as tubulin polymerization inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 484-499
作者:  Sun, Bin;  Li, Lin;  Hu, Qing-wen;  Xie, Fei;  Zheng, Hong-bo
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/16
Knockdown of Tubulin Polymerization Promoting Protein Family Member 3 Suppresses Proliferation and Induces Apoptosis in Non-Small-Cell Lung Cancer 期刊论文
JOURNAL OF CANCER, 2016, 卷号: 7, 期号: 10, 页码: 1189-1196
作者:  Li, Yintao;  Xu, Yali;  Ye, Kuanping;  Wu, Nan;  Li, Junfeng
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/16


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