Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain | |
Zhao, Wei; He, Long; Xiang, Tian-Le; Tang, Ya-Jie | |
刊名 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2019 | |
卷号 | 170页码:73-86 |
关键词 | Tubulin Colchicine domain Podophyllotoxin Binding affinity Nanomolar-potency antitumor activity |
DOI | 10.1016/j.ejmech.2019.03.006 |
URL标识 | 查看原文 |
公开日期 | [db:dc_date_available] |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/4536644 |
专题 | 山东大学 |
作者单位 | 1.Shandong Univ, State Key Lab Microbial Technol, Qingdao 266237, Shandong, Peoples R China. 2.Hubei |
推荐引用方式 GB/T 7714 | Zhao, Wei,He, Long,Xiang, Tian-Le,et al. Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2019,170:73-86. |
APA | Zhao, Wei,He, Long,Xiang, Tian-Le,&Tang, Ya-Jie.(2019).Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,170,73-86. |
MLA | Zhao, Wei,et al."Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain".EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 170(2019):73-86. |
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