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CORC

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Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus 期刊论文
MOLECULAR MICROBIOLOGY, 2020, 页码: 20
作者:  Yang, Nana;  Cao, Qiao;  Hu, Shuyang;  Xu, Chenchen;  Fan, Ke
收藏  |  浏览/下载：132/0  |  提交时间：2020/07/01
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua
收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01
Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 26, 页码: 23018-23025
作者:  Zhang, Yu;  Zhang, Yujie;  Guo, Qin;  Guo, Zhongyuan;  Chen, Xinli
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 161, 页码: 543-558
作者:  Yu, Jianjun;  Xu, Lei;  Hong, Duidui;  Zhang, Xiaotuan;  Liu, Jieyu
收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08
Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704
作者:  Qin, Chong;  Hu, Yang;  Zhou, Bing;  Fernandez-Salas, Ester;  Yang, Chao-Yie
收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 1056-1070
作者:  Zhuang, Rangxiao;  Gao, Lixin;  Lv, Xiaoqing;  Xi, Jianjun;  Sheng, Li
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08

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