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上海药物研究所 [71]
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期刊论文 [71]
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2021 [13]
2020 [18]
2019 [12]
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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:
Jin, Tingting
;
Xu, Lei
;
Wang, Peipei
;
Hu, Xiaobei
;
Zhang, Runyuan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
Stimuli-Sheddable Nanomedicine Overcoming Pathophysiological Barriers for Potentiating Immunotherapy of Cancer
期刊论文
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2021, 卷号: 17, 期号: 8, 页码: 1486-1509
作者:
Wang, Jiaxin
;
Zhou, Mengxue
;
Chen, Fangmin
;
Liu, Xiao
;
Gao, Jin
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Cancer Immunotherapy
Tumor Microenvironment
Stimuli-Responsiveness
Sheddable Nanoparticles
Pathophysiological Barriers
Endogenous Stimuli-Activatable Nanomedicine for Immune Theranostics for Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 卷号: 31, 期号: 26, 页码: 30
作者:
Wang, Weiqi
;
Jin, Yilan
;
Liu, Xiao
;
Chen, Fangmin
;
Zheng, Xiaohua
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
cancer immunotherapy
immune diagnosis
nanomedicine
stimuli-responsive
tumor microenvironment
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
期刊论文
CELL METABOLISM, 2021, 卷号: 33, 期号: 6, 页码: 1221-+
作者:
Liu, Yi
;
Liang, Guanghao
;
Xu, Hongjiao
;
Dong, Wenxin
;
Dong, Ze
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  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 37
作者:
Saeed, Madiha
;
Chen, Fangming
;
Ye, Jiayi
;
Shi, Yang
;
Lammers, Twan
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  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
clinical translation
nanobiomaterials
nanovaccines
normalization cancer immunotherapy
primary and adaptive resistance
tumor immune microenvironment
The ups, downs and new trends of IDO1 inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 12
作者:
Chen, Shulun
;
Tan, Jing
;
Zhang, Ao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/08/17
Immunotherapy
Cancer
Indoleamine 2,3-dioxygenase
Tryptophan 2,3-dioxygenase
Inhibitors
Checkpoint Inhibitor
High-density lipoprotein modulates tumor-associated macrophage for chemoimmunotherapy of hepatocellular carcinoma
期刊论文
NANO TODAY, 2021, 卷号: 37, 页码: 11
作者:
Wang, Junyang
;
Zheng, Chao
;
Zhai, Yihui
;
Cai, Ying
;
Lee, Robert J.
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  |  
浏览/下载:38/0
  |  
提交时间:2021/06/11
Tumor-associated macrophages
High-density lipoproteins
Immunotherapy
Hepatocellular carcinoma
Immunosuppression
Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer
期刊论文
SMALL, 2021, 卷号: 17, 期号: 13, 页码: 11
作者:
Zhu, Qiurong
;
Sun, Fang
;
Li, Tianliang
;
Zhou, Mengxue
;
Ye, Jiayi
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2021/05/24
colorectal cancer
combinatory immunotherapy
immunogenic cell death
prodrug nanoparticles
second near‐
infrared fluorescence imaging
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Nanobiomaterial-based vaccination immunotherapy of cancer
期刊论文
BIOMATERIALS, 2021, 卷号: 270, 页码: 26
作者:
Chen, Fangmin
;
Wang, Yingjie
;
Gao, Jing
;
Saeed, Madiha
;
Li, Tianliang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Cancer immunotherapy
Nanovaccine
Lymph node-targeting
Biomimetic nanobiomaterials
Antitumor immune response
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