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上海药物研究所 [12]
重庆大学 [7]
武汉大学 [4]
湖南大学 [4]
四川大学 [3]
西安交通大学 [2]
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期刊论文 [48]
会议论文 [3]
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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/08/17
Mapping the exposure and sensitivity to heat wave events in China's megacities
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 755, 页码: 12
作者:
Wang, Juan
;
Meng, Bin
;
Pei, Tao
;
Du, Yunyan
;
Zhang, Jingqiu
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/03/15
Heat wave events
Exposure
Sensitivity
China
Weibo social media
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
;
Wang, Yun
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  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:
Hu, Chujiao
;
Zuo, Yu
;
Liu, Jingqiu
;
Xu, Heng
;
Liao, Weike
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Licochalcone A
Mutant IDH1
Selective inhibitor
A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats
期刊论文
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10
作者:
Li, Xin
;
Wu, Ming
;
Chen, Limin
;
Lu, Junyan
;
Li, Guo
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
FTY720
Sphingosine-1-phosphate
Cordyceps sinensis
Autosomal dominant polycystic kidney disease
Inflammation
Efficacy and safety of bupropion hydrochloride extended-release versus escitalopram oxalate in Chinese patients with major depressive disorder: Results from a randomized, double-blind, non-inferiority trial
期刊论文
JOURNAL OF AFFECTIVE DISORDERS, 2019, 卷号: 257
作者:
Shen Yifeng
;
Zhao Qian
;
Yu Yimin
;
Tan Yunlong
;
Zhang Honggeng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/04
Antidepressant
Clinical trials
Depression
Mood disorders
Pharmacotherapy
The effects of endothelium-specific CYP2J2 overexpression on the attenuation of retinal ganglion cell apoptosis in a glaucoma rat model
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 10
作者:
Huang, Jingqiu
;
Zhao, Qinshuo
;
Li, Mu
;
Duan, Qiming
;
Zhao, Yin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
retinal vasculature
senescence
microRNAs
MMPs
Clinical outcome and prognostic analysis of young adults nasopharyngeal carcinoma patients of a nonendemic area in intensity-modulated radiotherapy era.
期刊论文
Future oncology (London, England), 2019
作者:
Huang Yecai
;
Zhang Jingqiu
;
He Qiao
;
Lan Mei
;
Feng Mei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
IMRT
intensity-modulated
radiotherapy
nasopharyngeal
carcinoma
young
adults
patients
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483
作者:
Zhu, Kongkai
;
Jiang, Chengshi
;
Tao, Hongrui
;
Liu, Jingqiu
;
Zhang, Hua
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Resynthesis
Virtual screening
Molecular docking
Molecular dynamics simulation
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