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科研机构
上海药物研究所 [7]
西北高原生物研究所 [1]
兰州化学物理研究所 [1]
内容类型
期刊论文 [9]
发表日期
2021 [9]
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
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  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
Synthesis and biological evaluation of novel cabazitaxel analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 41, 页码: 12
作者:
Ren, Sumei
;
Zhang, Minmin
;
Wang, Yujie
;
Guo, Jia
;
Wang, Junfei
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  |  
浏览/下载:57/0
  |  
提交时间:2021/08/17
Tritium extraction
Hydrogen isotopes
Eutectic Pb-Li
Fusion fuel cycle
Cabazitaxel
Docetaxel
Taxel
Anticancer
Semi-synthesis
10-Deacetylbaccatin III
Cytotoxicity
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
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  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 3, 页码: 1649-1669
作者:
Song, Zilan
;
Wang, Xiyuan
;
Zhang, Yan
;
Gu, Wangting
;
Shen, Ancheng
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  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:
Qiu, Xiaqiu
;
Li, Yuanqing
;
Yu, Bin
;
Ren, Jie
;
Huang, Huidan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
CDK9
Antitumor
PROTAC
AML
Degrader
Isolation and structure elucidation of polysaccharides from fruiting bodies of mushroom Coriolus versicolor and evaluation of their immunomodulatory effects
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 166, 页码: 1387-1395
作者:
Zhang, Xue
;
Cai, Zhenyu
;
Mao, Haoyu
;
Hu, Pei
;
Li, Xiaojun
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  |  
浏览/下载:39/0
  |  
提交时间:2021/05/24
Coriolus versicolor
Polysaccharides
Chemical structure
NMR analysis
Methylation
Immunoregulatory effects
Beta-glucan
Genus Ribes Linn. (Grossulariaceae): A comprehensive review of traditional uses, phytochemistry, pharmacology and clinical applications
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 276
作者:
Sun, Qing
;
Wang, Na
;
Xu, Wenhua
;
Zhou, Huakun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/11/18
Ribes species
Grossulariaceae
Traditional uses
Phytochemistry
Pharmacology
Clinical application
Effects of 8-Amino-Isocorydine, a Derivative of Isocorydine, on Gastric Carcinoma Cell Proliferation and Apoptosis
期刊论文
Current Therapeutic Research, 2021, 期号: 94, 页码: 100624
作者:
lei song
;
junxi liu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/11/25
8-amino isocorydine, antioxidant, apoptosis, aporphine alkaloid, flow cytometry,gastric carcinoma
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