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Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie
收藏  |  浏览/下载:70/0  |  提交时间:2021/06/11
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Song, Jia-Li;  Wang, Yin-Yin
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
New 4-N-phenylaminoquinoline derivatives as antioxidant, metal chelating and cholinesterase inhibitors for Alzheimer's disease. 期刊论文
Bioorganic chemistry, 2019, 卷号: Vol.93, 页码: 103328
作者:  Rong Cai;  Li-Ning Wang;  Jing-Jing Fan;  Shang-Qi Geng;  Yu-Ming Liu
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/21
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors 期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:  Cheng, Zhi-Qiang;  Zhu, Kong-Kai;  Zhang, Juan;  Song, Jia-Li;  Muehlmann, Luis Alexandre
收藏  |  浏览/下载:48/0  |  提交时间:2019/01/08
Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer's Disease Agents Using Pharmacophore, 3D-QSAR and Molecular Docking Approaches 期刊论文
2017, 卷号: 22, 期号: 8
作者:  Pang, Xiaocong;  Fu, Hui;  Yang, Shilun;  Wang, Lin;  Liu, Ai-Lin
收藏  |  浏览/下载:10/0  |  提交时间:2020/01/04
The discovery of new acetylcholinesterase inhibitors derived from pharmacophore modeling, virtual screening, docking simulation and bioassays 期刊论文
MOLECULAR BIOSYSTEMS, 2016, 卷号: 12, 期号: 12, 页码: 3734-3742
作者:  Zhang, Yunqin;  Zhang, Shuqun;  Xu, Guowei;  Yan, Hui;  Pua, Yinglan
收藏  |  浏览/下载:29/0  |  提交时间:2017/02/14
Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 4, 页码: 672-680
作者:  Luo, Wen[1];  Chen, Ying[2];  Wang, Ting[3];  Hong, Chen[4];  Chang, Li-Ping[5]
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/23
Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 17-26
作者:  Luo Wen[1];  Wang Ting[2];  Hong Chen[3];  Yang Ya-Chen[4];  Chen Ying[5]
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/23
Comparative Analysis of Amaryllidaceae Alkaloids from Three Lycoris Species 期刊论文
MOLECULES, 2015, 卷号: 20, 期号: 12, 页码: 21854-21869
作者:  Tian, Yongqiang;  Zhang, Chunyun;  Guo, Mingquan
收藏  |  浏览/下载:11/0  |  提交时间:2017/04/13
Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation 期刊论文
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2015, 卷号: 133, 期号: 0, 页码: 122-131
作者:  Yu, Yinhang;  Bai, Fuliang;  Wang, Wenfei;  Liu, Yaonan;  Yuan, Qingyan
收藏  |  浏览/下载:46/0  |  提交时间:2015/09/08


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