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CORC

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Allosteric Modulation: Dynamics is Double-"E"dged 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3694-3696
作者:  Xiong, Bing
收藏  |  浏览/下载：14/0  |  提交时间：2021/06/11
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：125/0  |  提交时间：2021/05/24
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:  Liu, Na;  Yang, Rui;  Shi, Ying;  Chen, Ling;  Liu, Yating
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/21
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433
作者:  Guo, Zuhao;  Zhang, Zhuqing;  Yang, Hong;  Cao, Danyan;  Xu, Xiaowei
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
The arginine methyltransferase PRMT5 and PRMT1 distinctly regulate the degradation of anti-apoptotic protein CFLAR(L) in human lung cancer cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1
作者:  Li, Mingyue;  An, Wentao;  Xu, Linyan;  Lin, Yidan;  Su, Ling
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/11
CFLAR  PRMT1  PRMT5  ITCH  Apoptosis  
Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617
作者:  Zheng, Bai-Nan;  Ding, Chen-Hong;  Chen, Shi-Jie;  Zhu, Kongkai;  Shao, Jingwei
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载：99/0  |  提交时间：2019/01/08

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