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Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Biological roles of LSD1 beyond its demethylase activity
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:
Gu, Feiying
;
Lin, Yuxin
;
Wang, Zhun
;
Wu, Xiaoxin
;
Ye, Zhenyue
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/11/26
LSD1
Demethylase
Ubiquitylation
FBXW7
Non-catalytic
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3
期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 10, 页码: 649-658
作者:
Hong, Feng
;
Zhao, Mengxue
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
dopaminergic neurons
Ezh2
Nurr1
neural stem cells
Distal-less homeobox 5 promotes the osteo-/dentinogenic differentiation potential of stem cells from apical papilla by activating histone demethylase KDM4B through a positive feedback mechanism
期刊论文
Experimental Cell Research, 2019, 卷号: Vol.374 No.1, 页码: 221-230
作者:
Haoqing Yang
;
Jiao Fan
;
Yangyang Cao
;
Runtao Gao
;
Zhipeng Fan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/13
Osteo-/dentinogenic
differentiation
Lysine-specific
demethylase
4B
(KDM4B)
Distal-less
homeobox
5
(DLX5)
Stem
cells
from
apical
papilla
(SCAPs)
Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts
期刊论文
BONE RESEARCH, 2018, 卷号: 6, 期号: 14, 页码: -
作者:
Sun, Jun
;
Niu, Ningning
;
Yan, Guang
;
Yang, Yang
;
Zou, Weiguo
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/04/28
Mesenchymal Stem-cells
Brachydactyly Type A2
Gene-expression
Differentiation
Activation
Mouse
Methylation
Repression
Mutations
Leukemia
Repressive effects of LSD1 inhibitor pargyline on cellular proliferation, motility and EMT process of prostate cancer in vitro
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 卷号: 11, 期号: 9
作者:
Zhang, Lu
;
Liu, Xiuheng
;
Wang, Min
;
Wang, Lei
;
Chen, Hui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Epithelial-mesenchymal-transition
lysine-specific demethylase 1
pargyline
prostate cancer
tumor-suppressor
Lysine-specific demethylase 2 contributes to the proliferation of small cell lung cancer by regulating the expression of TFPI-2
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 期号: 1, 页码: 733-740
作者:
Cao, Yunfeng
;
Guo, Chunhui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
lysine-specific demethylase 2
tissue factor pathway inhibitor-2
small
cell lung cancer
methylation
Inhibition of lysine-specific demethylase 1 prevents proliferation and mediates cisplatin sensitivity in ovarian cancer cells
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 6, 页码: 9025-9032
作者:
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
lysine-specific demethylase 1
proliferation
apoptosis
cisplatin
ovarian cancer
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 3, 页码: 1666-1676
作者:
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
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