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Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:  Sun, Dongxue;  Gao, Xiaoxia;  Wang, Qiao;  Krausz, Kristopher W.;  Fang, Zhongze
收藏  |  浏览/下载:44/0  |  提交时间:2021/11/04
Tailored nanodisc immobilization for one-step purification and reconstitution of cytochrome P450: A tool for membrane proteins' hard cases 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 12
作者:  Zhao, Lan;  Tao, Jiaoli;  Huang, Yongdong;  Zhu, Kai;  Du, Yuxiang
收藏  |  浏览/下载:59/0  |  提交时间:2021/08/31
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor 期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:  Zhang, Leduo;  Mao, Yu;  Gao, Zhiwei;  Chen, Xiaoyan;  Li, Xin
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/01
Establishment of rat liver microsome-hydrogel system for in vitro phase II metabolism and its application to study pharmacological effects of UGT substrates 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2019, 卷号: 34, 期号: 2
作者:  Zhang, Zhe;  Ma, Guo;  Xue, Caifu;  Sun, Hong;  Wang, Ziteng
收藏  |  浏览/下载:18/0  |  提交时间:2019/12/05
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties 期刊论文
Investigational New Drugs, 2019
作者:  Wu J.-D.;  Cui Y.-J.;  Zhou Y.-G.;  Tang L.-Q.;  Zhang C.-M.
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/11
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan
收藏  |  浏览/下载:234/0  |  提交时间:2019/01/08
Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9177-9204
作者:  Li, Daqiang;  Zhang, Xiaotuan;  Ma, Xiaodong;  Xu, Lei;  Yu, Jianjun
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Strategy for Hepatotoxicity Prediction Induced by Drug Reactive Metabolites Using Human Liver Microsome and Online 2D-Nano-LC-MS Analysis 期刊论文
ANALYTICAL CHEMISTRY, 2017, 卷号: 89, 期号: 24, 页码: 13167-13175
作者:  Zhuo, Yue;  Wu, Jian-Lin;  Yan, Xiaojing;  Guo, Ming-Quan;  Liu, Ning
收藏  |  浏览/下载:85/0  |  提交时间:2017/12/31
Discovery of a widespread metabolic pathway within and among phenolic xenobiotics 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Ashrap, Pahriya; Zheng, Guomao; Wan, Yi; Li, Tong; Hu, Wenxin; Li, Wenjuan; Zhang, Hong; Zhang, Zhaobin; Hu, Jianying
收藏  |  浏览/下载:32/0  |  提交时间:2017/12/03
Characterization of major metabolites of polymethoxylated flavonoids in Pericarpium Citri Reticulatae using liver microsomes immobilized on magnetic nanoparticles coupled with UPLC/MS-MS 期刊论文
CHEMISTRY CENTRAL JOURNAL, 2017, 卷号: 11, 页码: 13(1-10)
作者:  Liu, YM;  Lei, J;  Liao, X (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China.;  Liao, X;  Xue, Y
收藏  |  浏览/下载:12/0  |  提交时间:2018/08/28


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