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上海药物研究所 [14]
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厦门大学 [2]
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期刊论文 [41]
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Computational Biotransformation Profile of Emerging Phenolic Pollutants by Cytochromes P450: Phenol-Coupling Mechanism
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 5, 页码: 2902-2912
作者:
Guo, Fangjie
;
Chai, Lihong
;
Zhang, Shubin
;
Yu, Haiying
;
Liu, Weiping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/03/24
Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats
期刊论文
2019, 卷号: 10, 页码: 631
作者:
Zhang, Ziqian
;
Liu, Dandan
;
Jiang, Jianwei
;
Song, Xiuyun
;
Zou, Xiaowen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/01/03
drug metabolism
pharmacokinetic/pharmacodynamics (PK/PD)
UDP-glucuronosyltransferases
cytochromes P450
cerebral ischemia
neuroprotection
IMM-H004
Diversity and evolution of cytochromes P450 in stramenopiles
期刊论文
PLANTA, 2019, 卷号: 249, 期号: 3, 页码: 647-661
作者:
Teng, Linhong[1]
;
Fan, Xiao[2]
;
Nelson, David R.[3]
;
Han, Wentao[4]
;
Zhang, Xiaowen[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/02
Cytochrome P450
Comparative genomics
Molecular evolution
Stramenopiles
Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate
期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:
Hou, Xiangyu
;
Zhou, Jialan
;
Yu, Songda
;
Zhou, Lei
;
Zhang, Yifan
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  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
In vitrometabolic mapping of neobavaisoflavone in human cytochromes P450 and UDP-glucuronosyltransferase enzymes by ultra high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry
期刊论文
2018, 卷号: 158, 页码: 351
作者:
Xu, Jinjin[1]
;
Li, Mengsen[1]
;
Yao, Zhihong[1,2]
;
Zhang, Yezi[1]
;
Li, Shishi[1]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/10
Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity
期刊论文
2018, 卷号: 8, 期号: 19, 页码: 5246
作者:
Zhang, Tianpeng[1,2,3]
;
Yu, Fangjun[1]
;
Guo, Lianxia[1]
;
Chen, Min[1]
;
Yuan, Xue[1]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
Conditionally reprogrammed human normal bronchial epithelial cells express comparable levels of cytochromes p450 and are sensitive to BaP induction
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 3
作者:
Zhang, Zhengbao
;
Bai, Qing
;
Chen, Yu
;
Ye, Lina
;
Wu, Xiaoting
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Human normal bronchial epithelial cells
Conditional reprogramming (CR) technique
Cytochrome P450 (CYP)
Benzo(a)pyrene (BaP)
Toxicity testing
Reactivity Patterns of (Protonated) CompoundII and CompoundI of Cytochrome P450: Which is the Better Oxidant?
期刊论文
Chemistry - A European Journal, 2017, 卷号: 23, 期号: 26, 页码: 6406-6418
作者:
Li, Xiao-Xi
;
Verknica Postils
;
Sun, Wei
;
AbayomiS.Faponle
;
Miquel Sola
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/07/10
cytochrome P450
density functional calculations
electronic structure
hydroxylation
oxidation
Discovery of a widespread metabolic pathway within and among phenolic xenobiotics
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Ashrap, Pahriya
;
Zheng, Guomao
;
Wan, Yi
;
Li, Tong
;
Hu, Wenxin
;
Li, Wenjuan
;
Zhang, Hong
;
Zhang, Zhaobin
;
Hu, Jianying
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2017/12/03
triclosan
phenolic xenobiotic
liver microsome
metabolic kinetics
cross-talk reaction
CONSTITUTIVE ANDROSTANE RECEPTOR
REGULATING TRICLOSAN
UNITED-STATES
BISPHENOL-A
METHYL TRICLOSAN
CYTOCHROMES P450
ENZYMES
LIVER
TRICLOCARBAN
INDUCTION
Cytochromes P450 Inhibitory Excipient-Based Self-Microemulsions for the Improved Bioavailability of Protopanaxatriol and Protopanaxadiol: Preparation and Evaluation
期刊论文
2017, 卷号: 83, 期号: 5, 页码: 453-460
作者:
Yang, Feifei
;
Zhou, Jing
;
Liu, Chunyu
;
Hu, Xiao
;
Pan, Ruile
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/04
protopanaxatriol (PPT)
protopanaxadiol (PPD)
self-microemulsion
CYP450
oral bioavailability
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